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HNRNPH1 Polyclonal Antibody

HNRNPH1 Antibody in Immunocytochemistry (ICC/IF)

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HNRNPH1 Antibody (14774-1-AP) in ICC/IF

Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HepG2 cells using 14774-1-AP (HNRNPH1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

HNRNPH1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

14774-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

View 5 publications 5 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

View 1 publication 1 publication

RNA Immunoprecipitation (RIP)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

HNRNPH1 Fusion Protein Ag6506 (104-449 aa encoded by BC001348)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.35 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: SPDTANDGF VRLRGLPFGC SKEEIVQFFS GLEIVPNGIT LPVDFQGRST GEAFVQFASQ EIAEKALKKH KERIGHRYIE IFKSSRAEVR THYDPPRKLM AMQRPGPYDR PGAGRGYNSI GRGAGFERMR RGAYGGGYGG YDDYNGYNDG YGFGSDRFGR DLNYCFSGMS DHRYGDGGST FQSTTGHCVH MRGLPYRATE NDIYNFFSPL NPVRVHIEIG PDGRVTGEAD VEFATHEDAV AAMSKDKANM QHRYVELFLN STAGASGGAY EHRYVELFLN STAGASGGAY GSQMMGGMGL SNQSSYGGPA SQQLSGGYGG GYGGQSSMSG YDQVLQENSS DFQSNIA (104-449 aa encoded by BC001348 )

Target Information

This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some may shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNA and is very similar to the family member HNRPF. This gene may be associated with hereditary lymphedema type I. Alternatively spliced transcript variants have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Selective sorting and secretion of hY4 RNA fragments into extracellular vesicles mediated by methylated YBX1 to promote lung cancer progression.

Journal of experimental & clinical cancer research : CR

Li C,Wang W,Sun Y,Ni Y,Qin F,Li X,Wang T,Guo M,Sun G

Mon Apr 11 00:00:00 EDT 2022

C9orf72 Hexanucleotide Repeat Expansion-Related Neuropathology Is Attenuated by Nasal Rifampicin in Mice.

Biomedicines

Hatanaka Y,Umeda T,Shigemori K,Takeuchi T,Nagai Y,Tomiyama T

Fri May 06 00:00:00 EDT 2022

HnRNP F and hnRNP H1 regulate mRNA stability of amyloid precursor protein.

Neuroreport

Khan MI,Zhang J,Liu Q

Wed Jun 09 00:00:00 EDT 2021

HnRNP F and hnRNP H1 regulate mRNA stability of amyloid precursor protein.

Neuroreport

Khan MI,Zhang J,Liu Q

Wed Jun 09 00:00:00 EDT 2021

TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS.

Nature structural & molecular biology

Zuo X,Zhou J,Li Y,Wu K,Chen Z,Luo Z,Zhang X,Liang Y,Esteban MA,Zhou Y,Fu XD

Mon Feb 01 00:00:00 EST 2021

Corrigendum to article "Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation''.

Nucleic acids research

Chen R,Liu Y,Zhuang H,Yang B,Hei K,Xiao M,Hou C,Gao H,Zhang X,Jia C,Li L,Li Y,Zhang N

Mon Apr 19 00:00:00 EDT 2021

5' UTR variants in the quantitative trait gene Hnrnph1 support reduced 5' UTR usage and hnRNP H protein as a molecular mechanism underlying reduced methamphetamine sensitivity.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Ruan QT,Yazdani N,Reed ER,Beierle JA,Peterson LP,Luttik KP,Szumlinski KK,Johnson WE,Ash PEA,Wolozin B,Bryant CD

Wed Jul 01 00:00:00 EDT 2020

Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation.

Nucleic acids research

Chen R,Liu Y,Zhuang H,Yang B,Hei K,Xiao M,Hou C,Gao H,Zhang X,Jia C,Li L,Li Y,Zhang N

Fri Sep 29 00:00:00 EDT 2017

Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation.

Nucleic acids research

Chen R,Liu Y,Zhuang H,Yang B,Hei K,Xiao M,Hou C,Gao H,Zhang X,Jia C,Li L,Li Y,Zhang N

Fri Sep 29 00:00:00 EDT 2017

Transportin 1 accumulates specifically with FET proteins but no other transportin cargos in FTLD-FUS and is absent in FUS inclusions in ALS with FUS mutations.

Acta neuropathologica

Neumann M,Valori CF,Ansorge O,Kretzschmar HA,Munoz DG,Kusaka H,Yokota O,Ishihara K,Ang LC,Bilbao JM,Mackenzie IR

Thu Nov 01 00:00:00 EDT 2012

Transportin 1 accumulates specifically with FET proteins but no other transportin cargos in FTLD-FUS and is absent in FUS inclusions in ALS with FUS mutations.

Acta neuropathologica

Neumann M,Valori CF,Ansorge O,Kretzschmar HA,Munoz DG,Kusaka H,Yokota O,Ishihara K,Ang LC,Bilbao JM,Mackenzie IR

Thu Nov 01 00:00:00 EDT 2012

Bioinformatics

Protein Aliases: Heterogeneous nuclear ribonucleoprotein H; hnRNP H; Ratsg1

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Gene Aliases: AI642080; E430005G16Rik; Hnrnph; HNRNPH1; HNRPH; HNRPH1

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UniProt ID: (Human) P31943, (Mouse) O35737, (Rat) Q8VHV7

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Entrez Gene ID: (Human) 3187, (Mouse) 59013, (Rat) 140931

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Function(s)

nucleotide binding RNA binding protein binding poly(U) RNA binding poly(A) RNA binding nucleic acid binding RNA splicing factor

Process(es)

mRNA splicing, via spliceosome RNA processing fibroblast growth factor receptor signaling pathway gene expression regulation of RNA splicing mRNA processing RNA splicing

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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HNRNPH1 Polyclonal Antibody

HNRNPH1 Antibody (14774-1-AP) in ICC/IF

Product Details

14774-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

RNA Immunoprecipitation (RIP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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