Product References
The RNA-Binding Protein HuR Is Integral to the Function of Nociceptors in Mice and Humans.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Kunder N,de la Peña JB,Lou TF,Chase R,Suresh P,Lawson J,Shukla T,Black B,Campbell ZT
A-21277 was used in Immunohistochemistry (Frozen) to report an important mechanism of mRNA control in sensory neurons that ensures appropriate nociceptive responses to inflammatory mediators.
Wed Dec 07 00:00:00 EST 2022
Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation.
Nature cell biology
Huang H,Weng H,Sun W,Qin X,Shi H,Wu H,Zhao BS,Mesquita A,Liu C,Yuan CL,Hu YC,Hüttelmaier S,Skibbe JR,Su R,Deng X,Dong L,Sun M,Li C,Nachtergaele S,Wang Y,Hu C,Ferchen K,Greis KD,Jiang X,Wei M,Qu L,Guan JL,He C,Yang J,Chen J
Published figure using HuR monoclonal antibody (Product # A-21277) in Western Blot
Thu Mar 01 00:00:00 EST 2018
Elevated HuR in Pancreas Promotes a Pancreatitis-Like Inflammatory Microenvironment That Facilitates Tumor Development.
Molecular and cellular biology
Peng W,Furuuchi N,Aslanukova L,Huang YH,Brown SZ,Jiang W,Addya S,Vishwakarma V,Peters E,Brody JR,Dixon DA,Sawicki JA
A-21277 was used in Western Blotting to explore the consequences of human antigen R overexpression using a novel transgenic mouse model that has a >2-fold elevation of pancreatic HuR expression.
Thu Feb 01 00:00:00 EST 2018
Elevated HuR in Pancreas Promotes a Pancreatitis-Like Inflammatory Microenvironment That Facilitates Tumor Development.
Molecular and cellular biology
Peng W,Furuuchi N,Aslanukova L,Huang YH,Brown SZ,Jiang W,Addya S,Vishwakarma V,Peters E,Brody JR,Dixon DA,Sawicki JA
A-21277 was used in Western Blotting to explore the consequences of human antigen R overexpression using a novel transgenic mouse model that has a >2-fold elevation of pancreatic HuR expression.
Thu Feb 01 00:00:00 EST 2018
Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis.
Oncotarget
Blanco FF,Preet R,Aguado A,Vishwakarma V,Stevens LE,Vyas A,Padhye S,Xu L,Weir SJ,Anant S,Meisner-Kober N,Brody JR,Dixon DA
A21277 was used in immunohistochemistry - paraffin section to evaluate the effects of treating colorectal cancer cells with an HuR inhibitor
Tue Nov 08 00:00:00 EST 2016
Cigarette smoke enhances human rhinovirus-induced CXCL8 production via HuR-mediated mRNA stabilization in human airway epithelial cells.
Respiratory research
Hudy MH,Proud D
Published figure using HuR monoclonal antibody (Product # A-21277) in Western Blot
Fri Aug 30 00:00:00 EDT 2013
Localization of ribosomes and translation initiation factors to talin/beta3-integrin-enriched adhesion complexes in spreading and migrating mammalian cells.
Biology of the cell
Willett M,Pollard HJ,Vlasak M,Morley SJ
A-21277 was used in immunocytochemistry to discuss the effects of spatially localizing translation
Wed Feb 17 00:00:00 EST 2010
The mRNA binding proteins HuR and tristetraprolin regulate cyclooxygenase 2 expression during colon carcinogenesis.
Gastroenterology
Young LE,Sanduja S,Bemis-Standoli K,Pena EA,Price RL,Dixon DA
A-21277 was used in immunocytochemistry and immunohistochemistry - paraffin section to assess the functions of Hu antigen R and tristetraprolin during colon tumorigenesis
Fri May 01 00:00:00 EDT 2009
Regulation of non-AU-rich element containing c-fms proto-oncogene expression by HuR in breast cancer.
Oncogene
Woo HH,Zhou Y,Yi X,David CL,Zheng W,Gilmore-Hebert M,Kluger HM,Ulukus EC,Baker T,Stoffer JB,Chambers SK
A-21277 was used in immunohistochemistry and western blot to elucidate the role of RNA-binding proteins in breast cancer biology
Thu Mar 05 00:00:00 EST 2009
The role of AUF1 in thyroid carcinoma progression.
Endocrine-related cancer
Trojanowicz B,Brodauf L,Sekulla C,Lorenz K,Finke R,Dralle H,Hoang-Vu C
A-21277 was used in western blot to investigate the contribution of AUF1 to thyroid carcinoma progression
Tue Sep 01 00:00:00 EDT 2009
HuR expression in the nucleus correlates with high histological grade and poor disease-free survival in ovarian cancer.
The Australian & New Zealand journal of obstetrics & gynaecology
Yi X,Zhou Y,Zheng W,Chambers SK
A-21277 was used in immunohistochemistry - paraffin section to discuss the impact of HuR expression on ovarian cancer
Sun Feb 01 00:00:00 EST 2009
Activity-dependent expression of ELAV/Hu RBPs and neuronal mRNAs in seizure and cocaine brain.
Journal of neurochemistry
Tiruchinapalli DM,Caron MG,Keene JD
A-21277 was used in immunocytochemistry, immunohistochemistry (frozen), and western blot to determine the localization of HuR and HuD RNA-binding proteins after seizure or cocaine treatment.
Mon Dec 01 00:00:00 EST 2008
The peptidyl-prolyl isomerase Pin1 regulates granulocyte-macrophage colony-stimulating factor mRNA stability in T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950)
Esnault S,Shen ZJ,Whitesel E,Malter JS
A-21277 was used in immunoprecipitation investigate the role of Pin1 in the immune system
Wed Nov 15 00:00:00 EST 2006
The peptidyl-prolyl isomerase Pin1 regulates the stability of granulocyte-macrophage colony-stimulating factor mRNA in activated eosinophils.
Nature immunology
Shen ZJ,Esnault S,Malter JS
A-21277 was used in western blot to identify Pin1 as a factor that stabilizes granulocyte-macrophage colony-stimulating factor mRNA
Thu Dec 01 00:00:00 EST 2005
RhoB mRNA is stabilized by HuR after UV light.
Oncogene
Westmark CJ,Bartleson VB,Malter JS
A-21277 was used in immunocytochemistry, immunoprecipitation, and western blot to investigate how UV light affects RhoB mRNA stability
Thu Jan 13 00:00:00 EST 2005
Glucocorticoid inhibition of granulocyte macrophage-colony-stimulating factor from T cells is independent of control by nuclear factor-kappaB and conserved lymphokine element 0.
American journal of respiratory cell and molecular biology
Bergmann MW,Staples KJ,Smith SJ,Barnes PJ,Newton R
A-21277 was used in western blot to investigate GM-CSF expression in primary human T cells.
Thu Apr 01 00:00:00 EST 2004
Androgens regulate the binding of endogenous HuR to the AU-rich 3'UTRs of HIF-1alpha and EGF mRNA.
Biochemical and biophysical research communications
Sheflin LG,Zou AP,Spaulding SW
A-21277 was used in western blot to investigate the effect of androgen on the shuttling and AU-rich element-binding of endogenous HuR
Fri Sep 17 00:00:00 EDT 2004
ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5'UTR.
Genes & development
Kullmann M,Göpfert U,Siewe B,Hengst L
A-21277 was used in western blot to elucidate mechanisms of p27 translational regulation.
Sun Dec 01 00:00:00 EST 2002
