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DNA-binding protein that seems to act as a transcription factor (PubMed:19584537). Involved in the regulation of neuronal differentiation, acts upon JNK-signaling pathway activation and plays a role in neurite outgrowth in hippocampal cells. May mediate with FIBP FGF-signaling in the establishment of laterality in the embryo. Promotes cell motility, seems to stimulate tumor metastasis (PubMed:22120713). [UniProt]
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Protein Aliases: CHX1; chxI protein homolog; Cycloheximide-induced gene protein; Growth factor-inducible immediate early protein; Immediate early response gene 2 protein; Pip92; Proline-rich-induced protein 92; Protein ETR101; T-lymphocyte-activated protein
Gene Aliases: AI317238; Ch1; ETR101; IER2; PIP92
UniProt ID: (Human) Q9BTL4, (Rat) Q6P7D3, (Mouse) P17950
Entrez Gene ID: (Human) 9592, (Rat) 494344, (Mouse) 15936
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