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IL-7 Antibody (604-760) in IHC (P)
Immunohistochemistry: Human Tonsil (FFPE) stained with Mouse anti-IL-7 (Cat# 604-760) at 1:200 for 10 min @ RT. Staining of formalin-fixed tissue requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
Product Details
604-760
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rat
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
ZY335
Immunogen
A recombinant protein of human IL-7
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS with proprietary stabilizer
Contains
0.01% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
Product Specific Information
Positive control: Bone Marrow
Cellular location: Secreted.
Target Information
Interleukin 7 (IL-7) is a hematopoietic cytokine that is constitutively produced by stromal cells from the bone marrow and thymus. IL-7 signals through the IL-7R to promote the differentiation of hematopoietic stem cells to lymphoid precursor cells, which give rise to T cells, B cells, and natural killer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD127; CD127 antigen; CDw127; H-IL-7; IL-7; IL-7 receptor subunit alpha; IL-7R subunit alpha; ILN; Interleukin; interleukin 7 receptor alpha chain; interleukin 7 receptor isoform H5-6; Interleukin-7; Interleukin-7 receptor subunit alpha; Interleukin7; M-IL-7
Gene Aliases: CD127; CDW127; IL-7; IL-7R-alpha; IL7; IL7R; IL7RA; ILRA
UniProt ID: (Human) P13232, (Human) P16871
Entrez Gene ID: (Human) 3574, (Human) 3575
T cell lineage commitment
humoral immune response
cell-cell signaling
positive regulation of cell proliferation
organ morphogenesis
regulation of gene expression
positive regulation of B cell proliferation
negative regulation of apoptotic process
negative regulation of catalytic activity
bone resorption
positive regulation of T cell differentiation
positive regulation of organ growth
homeostasis of number of cells within a tissue
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
regulation of DNA recombination
cell morphogenesis
negative regulation of T cell mediated cytotoxicity
immunoglobulin production
immune response
signal transduction
cell surface receptor signaling pathway
regulation of cell size
positive regulation of gene expression
cell growth
T cell differentiation
positive regulation of T cell differentiation in thymus
interleukin-7-mediated signaling pathway
B cell proliferation
lymph node development
homeostasis of number of cells
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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