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Product Details
PA5-86992
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein of human IL17RD.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2803748
Product Specific Information
Purity is > 95% by SDS-PAGE.
Target Information
Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis. Might have a role in the early stages of fate specification of GnRH-secreting neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hSef; IL-17 receptor D; IL-17RD; IL17Rhom; Interleukin-17 receptor D; Interleukin-17 receptor-like protein; mSef; Sef homolog
Gene Aliases: 2810004A10Rik; AI428510; HH18; IL-17RD; IL17RD; IL17RLM; RGD1565237; SEF; Sef-S; UNQ6115/PRO20026
UniProt ID: (Human) Q8NFM7, (Mouse) Q8JZL1
Entrez Gene ID: (Human) 54756, (Rat) 498576, (Mouse) 171463
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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