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Proteintech
IgG light chain (Kappa) Polyclonal Antibody
Product Details
14678-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
IgG light chain (Kappa) Fusion Protein Ag6389 (1-234 aa encoded by BC030813)
Conjugate
Form
Liquid
Concentration
0.28 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody detects the light chain (Kappa) of human IgG.
Immunogen sequence: MEAPAQLLF LLLLWLPDTT GEIVMTQSPA TLSVSPGERA TLSCRASQSV TSNLAWYQQT PGQSPRLVIY GASSRASGVP ARFSGSGSGT EFTLTISSLQ SEDFAVYYCQ QYNKWPHTFG QGTKLDIKRT VAAPSVFIFP PSDEQLKSGT ASVVCLLNNF YPREAKVQWK VDNALQSGNS QESVTEQDSK DSTYSLSSTL TLSKADYEKH KVYACEVTHQ GLSSPVTKSF NRGEC (1-234 aa encoded by BC030813)
Target Information
Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five types) and two light chains (kappa, lambda; both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30. Antibodies to the kappa light chain are reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ig kappa chain c region; Immunoglobulin K; immunoglobulin kappa light chain; Kappa LC
Gene Aliases: HCAK1; Igk-C; IGK@; IGKCD; kappa; Km
Entrez Gene ID: (Human) 50802, (Human) 3514, (Mouse) 243469, (Mouse) 16071
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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