Proteintech

Insulin Polyclonal Antibody

Insulin Antibody in Immunocytochemistry (ICC/IF)

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Insulin Antibody (15848-1-AP) in ICC/IF

Immunofluorescent analysis of (4% PFA) fixed human pancreas tissue using (Product # 15848-1-AP) (INS antibody) at dilution of 1:100 and CoraLite594-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). The α cells of the islets of Langerhans was labelled in green with 67286-1-Ig (Glucagon antibody).

Insulin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Insulin Antibody in Immunohistochemistry (IHC)

Insulin Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

Product Image Gallery

Product Details

15848-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 15 publications 15 publications

Immunohistochemistry (IHC)

View 25 publications 25 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:250-1:1,000

Immunocytochemistry (ICC/IF)

1:250-1:1,000

View 23 publications 23 publications

Miscellaneous PubMed (Misc)

View 2 publications 2 publications

Not applicable (N/A)

View 3 publications 3 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Insulin Fusion Protein Ag8630 (1-110 aa encoded by BC005255)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.28 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MALWMRLLP LLALLALWGP DPAAAFVNQH LCGSHLVEAL YLVCGERGFF YTPKTRREAE DLQVGQVELG GGPGAGSLQP LALEGSLQKR GIVEQCCTSI CSLYQLENYC N (1-110 aa encoded by BC005255)

Target Information

Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Insulin is 51-amino acid polypeptide product produced from a precursor peptide, proinsulin. Proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds and one molecule of C-peptide. Insulin deficiency results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of b-cell origin such as insulinoma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Metabolomics analysis of islet regeneration in partial pancreatectomy mice reveals increased levels of long-chain fatty acids and activated cAMP signaling pathway.

Biochemical and biophysical research communications

Wu D,Jiang Y,Wang Z,Ni Y,Ma A,Zhou Y,Liu R,Lou YR,Wang Q

Sun Jul 30 00:00:00 EDT 2023

Metabolomics analysis of islet regeneration in partial pancreatectomy mice reveals increased levels of long-chain fatty acids and activated cAMP signaling pathway.

Biochemical and biophysical research communications

Wu D,Jiang Y,Wang Z,Ni Y,Ma A,Zhou Y,Liu R,Lou YR,Wang Q

Sun Jul 30 00:00:00 EDT 2023

Combined therapy of GABA and sitagliptin prevents high-fat diet impairment of beta-cell function.

Molecular and cellular endocrinology

Wang Z,Fan L,Ni Y,Wu D,Ma A,Zhao Y,Li J,Cui Q,Zhou Y,Zhang L,Lou YR,Prud'homme GJ,Wang Q

Sun Jan 01 00:00:00 EST 2023

Combined therapy of GABA and sitagliptin prevents high-fat diet impairment of beta-cell function.

Molecular and cellular endocrinology

Wang Z,Fan L,Ni Y,Wu D,Ma A,Zhao Y,Li J,Cui Q,Zhou Y,Zhang L,Lou YR,Prud'homme GJ,Wang Q

Sun Jan 01 00:00:00 EST 2023

Sulfated fuco-manno-glucuronogalactan alleviates pancreatic beta cell senescence via PI3K/AKT/FoxO1 pathway.

International journal of biological macromolecules

Zhang W,Wu N,Wang H,Mao G,Yan X,Zhang F,Linhardt RJ,Jin W,Zhou J

Mon May 01 00:00:00 EDT 2023

Secretory autophagy promotes RAB37-mediated insulin secretion under glucose stimulation both in vitro and in vivo.

Autophagy

Wu SY,Wu HT,Wang YC,Chang CJ,Shan YS,Wu SR,Chiu YC,Hsu CL,Juan HF,Lan KY,Chu CW,Lee YR,Lan SH,Liu HS

Sat Apr 01 00:00:00 EDT 2023

Secretory autophagy promotes RAB37-mediated insulin secretion under glucose stimulation both in vitro and in vivo.

Autophagy

Wu SY,Wu HT,Wang YC,Chang CJ,Shan YS,Wu SR,Chiu YC,Hsu CL,Juan HF,Lan KY,Chu CW,Lee YR,Lan SH,Liu HS

Sat Apr 01 00:00:00 EDT 2023

Icariin ameliorates memory deficits through regulating brain insulin signaling and glucose transporters in 3×Tg-AD mice.

Neural regeneration research

Yan F,Liu J,Chen MX,Zhang Y,Wei SJ,Jin H,Nie J,Fu XL,Shi JS,Zhou SY,Jin F

Sun Jan 01 00:00:00 EST 2023

Toceranib phosphate (Palladia) reverses type 1 diabetes by preserving islet function in mice.

The Journal of veterinary medical science

Kishi K,Yonezawa T,Kaji N,Goto M,Nonoshita Y,Iio A,Tsuru Y,Hori M

Mon Jul 17 00:00:00 EDT 2023

Shenlian (SL) Decoction, a Traditional Chinese Medicine Compound, May Ameliorate Blood Glucose via Mediating the Gut Microbiota in db/db Mice.

Journal of diabetes research

Sun RX,Huang WJ,Xiao Y,Wang DD,Mu GH,Nan H,Ni BR,Huang XQ,Wang HC,Liu YF,Fu Q,Zhao JX

Tue Mar 29 00:00:00 EDT 2022

Type IIB PKA is highly expressed in β cells and controls cell proliferation via regulating Cyclin D1 expression.

The FEBS journal

Jiang Y,Zhu L,Wu D,Ni Y,Huang C,Ye H,Yang Y,Liu R,Li Y

Sun May 01 00:00:00 EDT 2022

Cdc42 upregulation under high glucose induces podocyte apoptosis and impairs β-cell insulin secretion.

Frontiers in endocrinology

Jiang S,Xu CM,Yao S,Zhang R,Li XZ,Zhang RZ,Xie TY,Xing YQ,Zhang Q,Zhou XJ,Liao L,Dong JJ

Tue Aug 30 00:00:00 EDT 2022

ΔnFGF1 Protects β-Cells against High Glucose-Induced Apoptosis via the AMPK/SIRT1/PGC-1α Axis.

Oxidative medicine and cellular longevity

Chen Q,Chen X,Jia Z,Du Y,Zhang S,Xu W,Pan B,Lou J,Zhou J,Zhou J,Sun J

Fri Oct 14 00:00:00 EDT 2022

The potential mechanism of Liu-Wei-Di-Huang Pills in treatment of type 2 diabetic mellitus: from gut microbiota to short-chain fatty acids metabolism.

Acta diabetologica

Yi ZY,Chen L,Wang Y,He D,Zhao D,Zhang SH,Yu R,Huang JH

Sat Oct 01 00:00:00 EDT 2022

Experimental Periodontitis Deteriorates Cognitive Function and Impairs Insulin Signaling in a Streptozotocin-Induced Alzheimer's Disease Rat Model.

Journal of Alzheimer's disease : JAD

Duan L,Qian X,Wang Q,Huang L,Ge S

Thu Jul 07 00:00:00 EDT 2022

Engineering of hybrid spheroids of mesenchymal stem cells and drug depots for immunomodulating effect in islet xenotransplantation.

Science advances

Nguyen TT,Pham DV,Park J,Phung CD,Nepal MR,Pandit M,Shrestha M,Son Y,Joshi M,Jeong TC,Park PH,Choi DY,Chang JH,Kim JH,Kim JR,Kim IK,Yong CS,Kim JO,Sung JH,Jiang HL,Kim HS,Yook S,Jeong JH

Fri Aug 26 00:00:00 EDT 2022

Deficiency of M-LP/Mpv17L leads to development of β-cell hyperplasia and improved glucose tolerance via activation of the Wnt and TGF-β pathways.

Biochimica et biophysica acta. Molecular basis of disease

Iida R,Ueki M,Yasuda T

Tue Mar 01 00:00:00 EST 2022

Isolation of mouse pancreatic islet Procr⁺ progenitors and long-term expansion of islet organoids in vitro.

Nature protocols

Wang J,Wang D,Chen X,Yuan S,Bai L,Liu C,Zeng YA

Sun May 01 00:00:00 EDT 2022

Neu-P11 - a novel melatonin receptor agonist, could improve the features of type-2 diabetes mellitus in rats.

Endokrynologia Polska

Li X,He J,Li X,Li Y,Zhou Y,Cai S

Mon Mar 28 00:00:00 EDT 2022

Glucokinase Inactivation Paradoxically Ameliorates Glucose Intolerance by Increasing β-Cell Mass in db/db Mice.

Diabetes

Omori K,Nakamura A,Miyoshi H,Yamauchi Y,Kawata S,Takahashi K,Kitao N,Nomoto H,Kameda H,Cho KY,Terauchi Y,Atsumi T

Thu Apr 01 00:00:00 EDT 2021

SNAPIN Regulates Cell Cycle Progression to Promote Pancreatic β Cell Growth.

Frontiers in endocrinology

Jiang M,Kuang Z,He Y,Cao Y,Yu T,Cheng J,Liu W,Wang W

Thu Dec 16 00:00:00 EST 2021

SNAPIN Regulates Cell Cycle Progression to Promote Pancreatic β Cell Growth.

Frontiers in endocrinology

Jiang M,Kuang Z,He Y,Cao Y,Yu T,Cheng J,Liu W,Wang W

Thu Dec 16 00:00:00 EST 2021

SNAPIN Regulates Cell Cycle Progression to Promote Pancreatic β Cell Growth.

Frontiers in endocrinology

Jiang M,Kuang Z,He Y,Cao Y,Yu T,Cheng J,Liu W,Wang W

Thu Dec 16 00:00:00 EST 2021

HGF can reduce accumulation of inflammation and regulate glucose homeostasis in T2D mice.

Journal of physiology and biochemistry

Yan L,He X,Tang Y,Zhao X,Luo G,Wang X

Mon Nov 01 00:00:00 EDT 2021

Melatonin Promotes the Therapeutic Effect of Mesenchymal Stem Cells on Type 2 Diabetes Mellitus by Regulating TGF-β Pathway.

Frontiers in cell and developmental biology

Li B,Cheng X,Aierken A,Du J,He W,Zhang M,Tan N,Kou Z,Peng S,Jia W,Tang H,Hua J

Thu Feb 17 00:00:00 EST 2022

Advanced glycation end products activated endothelial-to-mesenchymal transition in pancreatic islet endothelial cells and triggered islet fibrosis in diabetic mice.

Chemico-biological interactions

Tsai PS,Chiu CY,Sheu ML,Yang CY,Lan KC,Liu SH

Wed Aug 25 00:00:00 EDT 2021

Mof acetyltransferase inhibition ameliorates glucose intolerance and islet dysfunction of type 2 diabetes via targeting pancreatic α-cells.

Molecular and cellular endocrinology

Guo X,Cui C,Song J,He Q,Zang N,Hu H,Wang X,Li D,Wang C,Hou X,Li X,Liang K,Yan F,Chen L

Mon Nov 01 00:00:00 EDT 2021

Glucokinase is required for high-starch diet-induced β-cell mass expansion in mice.

Journal of diabetes investigation

Tsuchida K,Nakamura A,Miyoshi H,Yang K,Yamauchi Y,Kawata S,Omori K,Takahashi K,Kitao N,Nomoto H,Kameda H,Cho KY,Seino Y,Terauchi Y,Atsumi T

Wed Sep 01 00:00:00 EDT 2021

Morphological and biochemical changes in the pancreas associated with acute systemic hypoxia.

Human cell

Morioka F,Tani N,Ikeda T,Hirokawa T,Ikeda K,Shida A,Aoki Y,Ishikawa T

Mon Mar 01 00:00:00 EST 2021

JunD Regulates Pancreatic β-Cells Function by Altering Lipid Accumulation.

Frontiers in endocrinology

Wang K,Cui Y,Lin P,Yao Z,Sun Y

Thu Dec 23 00:00:00 EST 2021

Nfe2l1 deficiency mitigates streptozotocin-induced pancreatic β-cell destruction and development of diabetes in male mice.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Bao S,Zheng H,Chen C,Zhang Y,Bao L,Yang B,Hou Y,Chen Y,Zhang Q,Pi J,Fu J

Wed Dec 01 00:00:00 EST 2021

12-Lipoxygenase governs the innate immune pathogenesis of islet inflammation and autoimmune diabetes.

JCI insight

Kulkarni A,Pineros AR,Walsh MA,Casimiro I,Ibrahim S,Hernandez-Perez M,Orr KS,Glenn L,Nadler JL,Morris MA,Tersey SA,Mirmira RG,Anderson RM

Thu Jul 22 00:00:00 EDT 2021

Meteorin-Like Ameliorates β Cell Function by Inhibiting β Cell Apoptosis of and Promoting β Cell Proliferation via Activating the WNT/β-Catenin Pathway.

Frontiers in pharmacology

Hu W,Wang R,Sun B

Tue Apr 06 00:00:00 EDT 2021

Long-Term Expansion of Pancreatic Islet Organoids from Resident Procr⁺ Progenitors.

Cell

Wang D,Wang J,Bai L,Pan H,Feng H,Clevers H,Zeng YA

Thu Mar 19 00:00:00 EDT 2020

Circular RNA circPPM1F modulates M1 macrophage activation and pancreatic islet inflammation in type 1 diabetes mellitus.

Theranostics

Zhang C,Han X,Yang L,Fu J,Sun C,Huang S,Xiao W,Gao Y,Liang Q,Wang X,Luo F,Lu W,Zhou Y

Mon May 31 00:00:00 EDT 2021

Localized Controlled Release of Bilirubin from β-Cyclodextrin-Conjugated ε-Polylysine To Attenuate Oxidative Stress and Inflammation in Transplanted Islets.

ACS applied materials & interfaces

Yao Q,Huang ZW,Zhai YY,Yue M,Luo LZ,Xue PP,Han YH,Xu HL,Kou L,Zhao YZ

Wed Feb 05 00:00:00 EST 2020

FABP4 inhibitor attenuates inflammation and endoplasmic reticulum stress of islet in leptin receptor knockout rats.

European review for medical and pharmacological sciences

Yao F,Jiang DD,Guo WH,Guo LS,Gao MM,Bai Y,Wang X,Zhang LS

Tue Dec 01 00:00:00 EST 2020

The MEK Inhibitor Trametinib Suppresses Major Histocompatibility Antigen-mismatched Rejection Following Pancreatic Islet Transplantation.

Transplantation direct

Tada S,Anazawa T,Shindo T,Yamane K,Inoguchi K,Fujimoto N,Nagai K,Masui T,Okajima H,Takaori K,Sumi S,Uemoto S

Tue Sep 01 00:00:00 EDT 2020

Islet transplantation in the subcutaneous space achieves long-term euglycaemia in preclinical models of type 1 diabetes.

Nature metabolism

Yu M,Agarwal D,Korutla L,May CL,Wang W,Griffith NN,Hering BJ,Kaestner KH,Velazquez OC,Markmann JF,Vallabhajosyula P,Liu C,Naji A

Thu Oct 01 00:00:00 EDT 2020

Depletion of the diabetic gut microbiota resistance enhances stem cells therapy in type 1 diabetes mellitus.

Theranostics

Lv W,Graves DT,He L,Shi Y,Deng X,Zhao Y,Dong X,Ren Y,Liu X,Xiao E,Zhang Y

Wed Apr 28 00:00:00 EDT 2021

Mint3 is dispensable for pancreatic and kidney functions in mice.

Biochemistry and biophysics reports

Chung Y,Saitoh Y,Hayashi T,Fukui Y,Terada N,Seiki M,Murakami Y,Sakamoto T

Tue Dec 01 00:00:00 EST 2020

Tectorigenin enhances PDX1 expression and protects pancreatic β-cells by activating ERK and reducing ER stress.

The Journal of biological chemistry

Yao X,Li K,Liang C,Zhou Z,Wang J,Wang S,Liu L,Yu CL,Song ZB,Bao YL,Zheng LH,Sun Y,Wang G,Huang Y,Yi J,Sun L,Li Y

Fri Sep 11 00:00:00 EDT 2020

Tectorigenin enhances PDX1 expression and protects pancreatic β-cells by activating ERK and reducing ER stress.

The Journal of biological chemistry

Yao X,Li K,Liang C,Zhou Z,Wang J,Wang S,Liu L,Yu CL,Song ZB,Bao YL,Zheng LH,Sun Y,Wang G,Huang Y,Yi J,Sun L,Li Y

Fri Sep 11 00:00:00 EDT 2020

Salsalate Prevents β-Cell Dedifferentiation in OLETF Rats with Type 2 Diabetes through Notch1 Pathway.

Aging and disease

Han F,Li X,Yang J,Liu H,Zhang Y,Yang X,Yang S,Chang B,Chen L,Chang B

Thu Aug 01 00:00:00 EDT 2019

TLR4 gene in the regulation of periodontitis and its molecular mechanism.

Experimental and therapeutic medicine

Qi W,Yang X,Ye N,Li S,Han Q,Huang J,Wu B

Sun Sep 01 00:00:00 EDT 2019

Rotenone protects against β-cell apoptosis and attenuates type 1 diabetes mellitus.

Apoptosis : an international journal on programmed cell death

Wu M,Chen W,Zhang S,Huang S,Zhang A,Zhang Y,Jia Z

Sun Dec 01 00:00:00 EST 2019

Rotenone protects against β-cell apoptosis and attenuates type 1 diabetes mellitus.

Apoptosis : an international journal on programmed cell death

Wu M,Chen W,Zhang S,Huang S,Zhang A,Zhang Y,Jia Z

Sun Dec 01 00:00:00 EST 2019

Using Recombinant Human Collagen With Basic Fibroblast Growth Factor to Provide a Simulated Extracellular Matrix Microenvironment for the Revascularization and Attachment of Islets to the Transplantation Region.

Frontiers in pharmacology

Zhu Q,Lu C,Jiang X,Yao Q,Jiang X,Huang Z,Jiang Y,Peng L,Fu H,Zhao Y

Tue Sep 29 00:00:00 EDT 2020

Frontiers in pharmacology

Zhu Q,Lu C,Jiang X,Yao Q,Jiang X,Huang Z,Jiang Y,Peng L,Fu H,Zhao Y

Tue Sep 29 00:00:00 EDT 2020

Upregulation of vitamin D-binding protein is associated with changes in insulin production in pancreatic beta-cells exposed to p,p'-DDT and p,p'-DDE.

Scientific reports

Pavlíková N,Daniel P,Šrámek J,Jelínek M,Šrámková V,Němcová V,Balušíková K,Halada P,Kovář J

Mon Dec 02 00:00:00 EST 2019

Expression of P2X1 receptors in somatostatin-containing cells in mouse gastrointestinal tract and pancreatic islets of both mouse and human.

Purinergic signalling

Ji R,Zhu J,Wang D,Sui QQ,Knight GE,Burnstock G,Yuan H,Xiang Z

Sat Sep 01 00:00:00 EDT 2018

Expression of P2X1 receptors in somatostatin-containing cells in mouse gastrointestinal tract and pancreatic islets of both mouse and human.

Purinergic signalling

Ji R,Zhu J,Wang D,Sui QQ,Knight GE,Burnstock G,Yuan H,Xiang Z

Sat Sep 01 00:00:00 EDT 2018

The Synergy of Two Factors on Insulin Expression.

Cellular reprogramming

Luo Y,Xu Y,Wang ZY,Li X,Xing WB,Zhang TC

Thu Feb 01 00:00:00 EST 2018

The Synergy of Two Factors on Insulin Expression.

Cellular reprogramming

Luo Y,Xu Y,Wang ZY,Li X,Xing WB,Zhang TC

Thu Feb 01 00:00:00 EST 2018

AWRK6, a Novel GLP-1 Receptor Agonist, Attenuates Diabetes by Stimulating Insulin Secretion.

International journal of molecular sciences

Wang Q,Zhao C,Jin L,Zhang H,Miao Q,Liu H,Zhang D

Sun Oct 07 00:00:00 EDT 2018

AWRK6, a Novel GLP-1 Receptor Agonist, Attenuates Diabetes by Stimulating Insulin Secretion.

International journal of molecular sciences

Wang Q,Zhao C,Jin L,Zhang H,Miao Q,Liu H,Zhang D

Sun Oct 07 00:00:00 EDT 2018

Hepatitis B X-interacting protein promotes the formation of the insulin gene-transcribing protein complex Pdx-1/Neurod1 in animal pancreatic β-cells.

The Journal of biological chemistry

Li H,Wang Z,Li Y,Fang R,Wang H,Shi H,Zhang X,Zhang W,Ye L

Fri Feb 09 00:00:00 EST 2018

Secretory expression and surface display of a new and biologically active single-chain insulin (SCI-59) analog by lactic acid bacteria.

Applied microbiology and biotechnology

Mao R,Wu D,Hu S,Zhou K,Wang M,Wang Y

Sat Apr 01 00:00:00 EDT 2017

Secretory expression and surface display of a new and biologically active single-chain insulin (SCI-59) analog by lactic acid bacteria.

Applied microbiology and biotechnology

Mao R,Wu D,Hu S,Zhou K,Wang M,Wang Y

Sat Apr 01 00:00:00 EDT 2017

Differential protein analysis of serum exosomes post-intravenous immunoglobulin therapy in patients with Kawasaki disease.

Cardiology in the young

Zhang L,Song QF,Jin JJ,Huang P,Wang ZP,Xie XF,Gu XQ,Gao XJ,Jia HL

Wed Nov 01 00:00:00 EDT 2017

Differential protein analysis of serum exosomes post-intravenous immunoglobulin therapy in patients with Kawasaki disease.

Cardiology in the young

Zhang L,Song QF,Jin JJ,Huang P,Wang ZP,Xie XF,Gu XQ,Gao XJ,Jia HL

Wed Nov 01 00:00:00 EDT 2017

Involvement of Insulin Signaling Disturbances in Bisphenol A-Induced Alzheimer's Disease-like Neurotoxicity.

Scientific reports

Wang T,Xie C,Yu P,Fang F,Zhu J,Cheng J,Gu A,Wang J,Xiao H

Tue Aug 08 00:00:00 EDT 2017

Involvement of Insulin Signaling Disturbances in Bisphenol A-Induced Alzheimer's Disease-like Neurotoxicity.

Scientific reports

Wang T,Xie C,Yu P,Fang F,Zhu J,Cheng J,Gu A,Wang J,Xiao H

Tue Aug 08 00:00:00 EDT 2017

Insulin signaling disruption in male mice due to perinatal bisphenol A exposure: Role of insulin signaling in the brain.

Toxicology letters

Fang F,Gao Y,Wang T,Chen D,Liu J,Qian W,Cheng J,Gao R,Wang J,Xiao H

Mon Mar 14 00:00:00 EDT 2016

Insulin signaling disruption in male mice due to perinatal bisphenol A exposure: Role of insulin signaling in the brain.

Toxicology letters

Fang F,Gao Y,Wang T,Chen D,Liu J,Qian W,Cheng J,Gao R,Wang J,Xiao H

Mon Mar 14 00:00:00 EDT 2016

Bisphenol A disrupts glucose transport and neurophysiological role of IR/IRS/AKT/GSK3β axis in the brain of male mice.

Environmental toxicology and pharmacology

Li J,Wang Y,Fang F,Chen D,Gao Y,Liu J,Gao R,Wang J,Xiao H

Fri Apr 01 00:00:00 EDT 2016

The effect of cholesteryl ester transfer protein on pancreatic beta cell dysfunction in mice.

Nutrition & metabolism

Guo W,Gong Y,Fu Z,Fu J,Sun Y,Ju X,Chang Y,Wang W,Zhu X,Gao B,Liu X,Yang T,Zhou H

Mon Mar 14 00:00:00 EDT 2016

The effect of cholesteryl ester transfer protein on pancreatic beta cell dysfunction in mice.

Nutrition & metabolism

Guo W,Gong Y,Fu Z,Fu J,Sun Y,Ju X,Chang Y,Wang W,Zhu X,Gao B,Liu X,Yang T,Zhou H

Mon Mar 14 00:00:00 EDT 2016

CNC-bZIP protein Nrf1-dependent regulation of glucose-stimulated insulin secretion.

Antioxidants & redox signaling

Zheng H,Fu J,Xue P,Zhao R,Dong J,Liu D,Yamamoto M,Tong Q,Teng W,Qu W,Zhang Q,Andersen ME,Pi J

Wed Apr 01 00:00:00 EDT 2015

CNC-bZIP protein Nrf1-dependent regulation of glucose-stimulated insulin secretion.

Antioxidants & redox signaling

Zheng H,Fu J,Xue P,Zhao R,Dong J,Liu D,Yamamoto M,Tong Q,Teng W,Qu W,Zhang Q,Andersen ME,Pi J

Wed Apr 01 00:00:00 EDT 2015

Effects of Bisphenol A on glucose homeostasis and brain insulin signaling pathways in male mice.

General and comparative endocrinology

Fang F,Chen D,Yu P,Qian W,Zhou J,Liu J,Gao R,Wang J,Xiao H

Sun Feb 01 00:00:00 EST 2015

Effects of Bisphenol A on glucose homeostasis and brain insulin signaling pathways in male mice.

General and comparative endocrinology

Fang F,Chen D,Yu P,Qian W,Zhou J,Liu J,Gao R,Wang J,Xiao H

Sun Feb 01 00:00:00 EST 2015

Silencing Mist1 Gene Expression Is Essential for Recovery from Acute Pancreatitis.

PloS one

Karki A,Humphrey SE,Steele RE,Hess DA,Taparowsky EJ,Konieczny SF

Sun Jun 26 00:00:00 EDT 2016

Silencing Mist1 Gene Expression Is Essential for Recovery from Acute Pancreatitis.

PloS one

Karki A,Humphrey SE,Steele RE,Hess DA,Taparowsky EJ,Konieczny SF

Sun Jun 26 00:00:00 EDT 2016

Autoimmune diabetes is suppressed by treatment with recombinant human tissue Kallikrein-1.

PloS one

Maneva-Radicheva L,Amatya C,Parker C,Ellefson J,Radichev I,Raghavan A,Charles ML,Williams MS,Robbins MS,Savinov AY

Wed Jun 10 00:00:00 EDT 2015

Autoimmune diabetes is suppressed by treatment with recombinant human tissue Kallikrein-1.

PloS one

Maneva-Radicheva L,Amatya C,Parker C,Ellefson J,Radichev I,Raghavan A,Charles ML,Williams MS,Robbins MS,Savinov AY

Wed Jun 10 00:00:00 EDT 2015

Display of human proinsulin on the Bacillus subtilis spore surface for oral administration.

Current microbiology

Feng F,Hu P,Chen L,Tang Q,Lian C,Yao Q,Chen K

Mon Jul 01 00:00:00 EDT 2013

Display of human proinsulin on the Bacillus subtilis spore surface for oral administration.

Current microbiology

Feng F,Hu P,Chen L,Tang Q,Lian C,Yao Q,Chen K

Mon Jul 01 00:00:00 EDT 2013

Tendons from non-diabetic humans and rats harbor a population of insulin-producing, pancreatic beta cell-like cells.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme

Lehner C,Gehwolf R,Wagner A,Resch H,Hirzinger C,Augat P,Stephan D,Aigner L,Rivera FJ,Bauer HC,Tempfer H

Fri Jun 01 00:00:00 EDT 2012

Tendons from non-diabetic humans and rats harbor a population of insulin-producing, pancreatic beta cell-like cells.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme

Lehner C,Gehwolf R,Wagner A,Resch H,Hirzinger C,Augat P,Stephan D,Aigner L,Rivera FJ,Bauer HC,Tempfer H

Fri Jun 01 00:00:00 EDT 2012

Tendons from non-diabetic humans and rats harbor a population of insulin-producing, pancreatic beta cell-like cells.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme

Lehner C,Gehwolf R,Wagner A,Resch H,Hirzinger C,Augat P,Stephan D,Aigner L,Rivera FJ,Bauer HC,Tempfer H

Fri Jun 01 00:00:00 EDT 2012

Bioinformatics

Protein Aliases: Ins; Insulin; Insulin-1; Insulin-2; preproinsulin; proinsulin

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Gene Aliases: AA986540; IDDM; IDDM1; IDDM2; ILPR; INS; Ins-1; Ins-2; Ins1; Ins2; Ins2-rs1; InsII; IRDN; Mody; MODY10; Mody4; proinsulin

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UniProt ID: (Human) P01308, (Rat) P01322, (Mouse) P01325, (Rat) P01323, (Mouse) P01326

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Entrez Gene ID: (Human) 3630, (Rat) 24505, (Mouse) 16333, (Rat) 24506, (Mouse) 16334

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Function(s)

protease binding insulin receptor binding insulin-like growth factor receptor binding hormone activity protein binding identical protein binding chaperone binding protein complex binding growth factor

Process(es)

Performance Guarantee

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Insulin Polyclonal Antibody

Insulin Antibody (15848-1-AP) in ICC/IF

Product Details

15848-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (PFA fixed) (IHC (PFA))

Immunocytochemistry (ICC/IF)

Miscellaneous PubMed (Misc)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

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