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Product Details
H00003714-M10
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
4G10
Immunogen
JAG2 (NP_002217, 121 a.a. approximately 210 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: AGGDQDPGLV VIPFQFAWPR SFTLIVEAWD WDNDTTPNEE LLIERVSHAG MINPEDRWKS LHFSGHVAHL ELQIRVRCDE NYYSAPCNKF
Target Information
The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. JAG2 is one of several ligands that activate Notch and related receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Jagged2; Protein jagged-2
Gene Aliases: HJ2; JAG2; SER2
UniProt ID: (Human) Q9Y219
Entrez Gene ID: (Human) 3714
skeletal system development
in utero embryonic development
respiratory system process
cell cycle
Notch signaling pathway
Notch receptor processing
spermatogenesis
auditory receptor cell fate commitment
morphogenesis of embryonic epithelium
cell differentiation
regulation of cell adhesion
T cell differentiation
regulation of cell migration
regulation of cell proliferation
odontogenesis of dentin-containing tooth
gamma-delta T cell differentiation
thymic T cell selection
positive regulation of Notch signaling pathway
epithelial cell apoptotic process involved in palatal shelf morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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