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Product Details
PA1-16916
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rabbit
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide between residues 1-100 of the human Jumonji protein.
Conjugate
Form
Liquid
Concentration
1.0 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2129067
Product Specific Information
PA1-16916 is specific for the ~140 kDa Jumonji protein.
Another band is seen >200 kDa and a faint band may be seen ~80 kDa.
Target Information
Jumonji (JARID2) is a nuclear protein that participates in the negative regulation of cell growth. It is required for neural tube formation and is essential for normal heart development and function. Also, it is a part of a group of proteins characterized by a novel structural motif, the JmjC domain, which is implicated in chromatin regulation through histone demethylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: JARD2 antibody; jumonji homolog; jumonji, AT rich interactive domain 2; jumonji, AT rich interactive domain 2 protein; jumonji-like protein; Jumonji/ARID domain-containing protein 2; Protein Jumonji
Gene Aliases: JARID2; JMJ; jumonji
UniProt ID: (Human) Q92833, (Mouse) Q62315
Entrez Gene ID: (Human) 3720, (Rabbit) 100339907, (Mouse) 16468
negative regulation of transcription from RNA polymerase II promoter
liver development
transcription, DNA-templated
central nervous system development
negative regulation of cell proliferation
covalent chromatin modification
negative regulation of histone methylation
negative regulation of gene expression, epigenetic
negative regulation of transcription, DNA-templated
spleen development
thymus development
stem cell differentiation
positive regulation of histone H3-K9 methylation
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
chromatin modification
cell differentiation
regulation of cell proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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