Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 2
JARID2 Antibody (MA5-52652) in ICC/IF
Immunocytochemistry analysis of JARID2 in HepG2 cells. Nuclei were stained blue with DAPI; JARID2 recombinant monoclonal antibody (Product # MA5-52652) with a dilution of 1:1,000 was stained magenta with Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
Product Details
MA5-52652
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
23GB4025
Immunogen
A synthesized peptide derived from Jarid2 (111-186AA).
Conjugate
Form
Liquid
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
Jumonji (JARID2) is a nuclear protein that participates in the negative regulation of cell growth. It is required for neural tube formation and is essential for normal heart development and function. Also, it is a part of a group of proteins characterized by a novel structural motif, the JmjC domain, which is implicated in chromatin regulation through histone demethylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: JARD2 antibody; jumonji homolog; jumonji, AT rich interactive domain 2; jumonji-like protein; Jumonji/ARID domain-containing protein 2; Protein Jumonji
Gene Aliases: JARID2; JMJ; jumonji
UniProt ID: (Human) Q92833, (Mouse) Q62315
Entrez Gene ID: (Human) 3720, (Mouse) 16468, (Rat) 681740
negative regulation of transcription from RNA polymerase II promoter
liver development
transcription, DNA-templated
central nervous system development
negative regulation of cell proliferation
covalent chromatin modification
negative regulation of histone methylation
negative regulation of gene expression, epigenetic
negative regulation of transcription, DNA-templated
spleen development
thymus development
stem cell differentiation
positive regulation of histone H3-K9 methylation
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
chromatin modification
cell differentiation
regulation of cell proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support