Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
PA5-28262
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Insect,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 1 and 424 of Human JNK2
Conjugate
Form
Liquid
Concentration
0.57 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2545738
Product Specific Information
Recommended positive controls: U87-MG, MCF-7.
Predicted reactivity: Mouse (99%), Rat (99%), Chicken (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
MAPK9 (JNK2) is a serine/threonine kinase which plays an important role in the MAPK pathway. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: c-Jun kinase 2; c-Jun N-terminal kinase 2; JNK; JNK-55; JNK/SAPK alpha; JNK1; JNK1A2; JNK21B1/2; Jun kinase; MAP kinase 9; MAPK 10; MAPK 9; MAPK10; MAPK8; mitogen activated protein kinase 9; Mitogen-activated protein kinase 9; OTTHUMP00000161542; OTTHUMP00000161543; p54-alpha; PRKM8; protein kinase, mitogen-activated 9; SAPK-alpha; SAPK1; SAPK1a; stress activated protein kinase alpha II; Stress-activated protein kinase 1a; Stress-activated protein kinase JNK2
Gene Aliases: AI851083; JNK-55; JNK2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; MAPK9; p54a; p54aSAPK; PRKM9; SAPK; SAPK1A
UniProt ID: (Human) P45984, (Rat) P49186, (Mouse) Q9WTU6
Entrez Gene ID: (Human) 5601, (Rat) 50658, (Mouse) 26420
JUN kinase activity
protein binding
ATP binding
transcription factor binding
cysteine-type endopeptidase activator activity involved in apoptotic process
mitogen-activated protein kinase kinase kinase binding
MAP kinase activity
nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
release of cytochrome c from mitochondria
positive regulation of protein phosphorylation
protein phosphorylation
protein targeting to mitochondrion
activation of cysteine-type endopeptidase activity involved in apoptotic process
response to stress
JNK cascade
JUN phosphorylation
central nervous system development
response to mechanical stimulus
response to toxic substance
positive regulation of gene expression
positive regulation of macrophage derived foam cell differentiation
positive regulation of cell morphogenesis involved in differentiation
response to amine
neuron projection development
positive regulation of prostaglandin biosynthetic process
regulation of protein ubiquitination
positive regulation of prostaglandin secretion
positive regulation of chemokine production
cellular response to UV
Fc-epsilon receptor signaling pathway
response to drug
regulation of circadian rhythm
positive regulation of nitric oxide biosynthetic process
positive regulation of transcription, DNA-templated
regulation of JNK cascade
response to cadmium ion
rhythmic process
regulation of sequence-specific DNA binding transcription factor activity
positive regulation of nitric-oxide synthase biosynthetic process
cellular response to lipopolysaccharide
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to growth factor stimulus
positive regulation of podosome assembly
positive regulation of apoptotic signaling pathway
MAPK cascade
response to organic substance
positive regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
phosphorylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support