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Product Details
PA5-20641
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 14 amino acid peptide near the carboxy terminus of human JPH2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11152695
Product Specific Information
A suggested positive control is 293 cell lysate.
PA5-20641 can be used with blocking peptide PEP-0761.
Target Information
This gene encodes a protein with a leucine-rich repeat and a calponin homology domain. Polymorphism in this gene may be associated with susceptibililty to knee osteoarthritis. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: JP-2; jph2 {ECO:0000312|RGD:1305196}; Junctophilin type 2; Junctophilin-2
Gene Aliases: 1110002E14Rik; CMH17; JP-2; JP2; JPH2
UniProt ID: (Human) Q9BR39, (Mouse) Q9ET78, (Rat) Q2PS20
Entrez Gene ID: (Human) 57158, (Mouse) 59091, (Rat) 296345
phosphatidylserine binding
protein binding
phosphatidylinositol-4,5-bisphosphate binding
phosphatidylinositol-3,4,5-trisphosphate binding
phosphatidylinositol-5-phosphate binding
calcium-release channel activity
phosphatidylinositol-3-phosphate binding
phosphatidylinositol-4-phosphate binding
phosphatidic acid binding
phosphatidylinositol-3,5-bisphosphate binding
positive regulation of cytosolic calcium ion concentration
multicellular organism development
regulation of cardiac muscle tissue development
calcium ion homeostasis
positive regulation of ryanodine-sensitive calcium-release channel activity
calcium ion transmembrane transport
release of sequestered calcium ion into cytosol
regulation of ryanodine-sensitive calcium-release channel activity
calcium ion transport into cytosol
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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