Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Several transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: K+ channel subunit; KSHIIIC; MGC126818; potassium channel, voltage gated Shaw related subfamily C, member 4; potassium voltage gated channel, Shaw-related subfamily, member 4; Potassium voltage-gated channel subfamily C member 4; potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (Raw3); potassium voltage-gated channel, Shaw-related subfamily, member 4; Raw3; Voltage-gated potassium channel KCNC4; Voltage-gated potassium channel subunit Kv3.4
Gene Aliases: AI850292; C1orf30; HKSHIIIC; KCNC4; Kcr2-4; KSHIIIC; KV3.4
UniProt ID: (Human) Q03721, (Mouse) Q8R1C0, (Rat) Q63734
Entrez Gene ID: (Human) 3749, (Mouse) 99738, (Rat) 684516
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