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KCNJ14 Antibody (PA5-103645) in IHC (P)
Immunohistochemistry analysis of KCNJ14 in rat testis tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with KCNJ14 polyclonal antibody (Product # PA5-103645) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-103645
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human KCNJ14(Accession Q9UNX9), corresponding to amino acid residues T386-P436.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2852979
Product Specific Information
Antibody detects endogenous levels of total KCNJ14.
Target Information
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ14 gives rise to low-conductance channels with a low affinity to the channel blockers Barium and Cesium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-sensitive inward rectifier potassium channel 14; Inward rectifier K(+) channel Kir2.4; inwardly rectifying potassium channel KIR2.4; IRK-4; IRK4; Potassium channel, inwardly rectifying subfamily J member 14; potassium channel, inwardly rectifying subfamily J, member 14; potassium inwardly-rectifying channel J14; potassium inwardly-rectifying channel, subfamily J, member 14
Gene Aliases: A930026G01Rik; IRK4; KCNJ14; KIR2.4
UniProt ID: (Human) Q9UNX9, (Rat) O70596, (Mouse) Q8JZN3
Entrez Gene ID: (Human) 3770, (Rat) 276720, (Mouse) 211480
Performance Guarantee
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