Invitrogen

KIAA1429 Polyclonal Antibody

4 Published Figures

3 References

View all (11) KIAA1429 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (3)
Published Figures (4)

KIAA1429 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 7

KIAA1429 Antibody (PA5-95717) in IHC (P)

Immunohistochemistry analysis of KIAA1429 in paraffin-embedded human esophageal cancer. Samples were incubated with KIAA1429 Polyclonal antibody (Product # PA5-95717) using a dilution of 1:200 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.

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Product Details

PA5-95717

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:5,000

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:100

Immunocytochemistry (ICC/IF)

1:50-1:100

RNA Immunoprecipitation (RIP)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1400-1700 of human KIAA1429 (NP_0563112)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.08 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2807519

Product Specific Information

Immunogen sequence: FMRQILNSDT IGCCGDDNGL MEVEGAHTSR TMSINAAELK QLLQSKEESP ENLFLELEKL VLEHSKDDDN LDSLLDSVVG LKQMLESSGD PLPLSDQDVE PVLSAPESLQ NLFNNRTAYV LADVMDDQLK SMWFTPFQAE EIDTDLDLVK VDLIELSEKC CSDFDLHSEL ERSFLSEPSS PGRTKTTKGF KLGKHKHETF ITSSGKSEYI EPAKRAHVVP PPRGRGRGGF GQGIRPHDIF RQRKQNTSRP PSMHVDDFVA AESKEVVPQD GIPPPKRPLK VSQKISSRGG FSGNRGGRGA F; Positive Samples: K-562, COS7, HeLa, PC-3

Target Information

KIAA1429 is required for N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and processing. It is also Involved in mRNA splicing regulation, probably via its function in m6A methylation. Diseases associated with KIAA1429 include Retinitis Pigmentosa 42.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

m⁶A Methyltransferase KIAA1429 Regulates the Cisplatin Sensitivity of Gastric Cancer Cells via Stabilizing FOXM1 mRNA.

Cancers

Zhu Z,Zhou Y,Chen Y,Zhou Z,Liu W,Zheng L,Pei Q,Tan F,Pei H,Li Y

Published figure using KIAA1429 polyclonal antibody (Product # PA5-95717) in Western Blot

Fri Oct 14 00:00:00 EDT 2022

m⁶A methyltransferase KIAA1429 acts as an oncogenic factor in colorectal cancer by regulating SIRT1 in an m⁶A-dependent manner.

Cell death discovery

Zhou Y,Pei Z,Maimaiti A,Zheng L,Zhu Z,Tian M,Zhou Z,Tan F,Pei Q,Li Y,Liu W

PA5-95717 was used in RNA Immunoprecipitation to suggest that the m6A methyltransferase KIAA1429 promotes the growth and motility of colorectal cancer and could be a potent therapeutic target.

Fri Feb 25 00:00:00 EST 2022

N⁶-methyladenosine (m⁶A) methyltransferase KIAA1429 accelerates the gefitinib resistance of non-small-cell lung cancer.

Cell death discovery

Tang J,Han T,Tong W,Zhao J,Wang W

PA5-95717 was used in Western Blotting to indicate that KIAA1429 plays essential oncogenic roles in gefitinib resistance, which may provide a feasible therapeutic target for non-small-cell lung cancer.

Mon May 17 00:00:00 EDT 2021

N⁶-methyladenosine (m⁶A) methyltransferase KIAA1429 accelerates the gefitinib resistance of non-small-cell lung cancer.

Cell death discovery

Tang J,Han T,Tong W,Zhao J,Wang W

Mon May 17 00:00:00 EDT 2021

Bioinformatics

Protein Aliases: DKFZP434I116; functional spliceosome-associated protein 121; Protein virilizer homolog

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Gene Aliases: 4930422M05Rik; fSAP121; KIAA1429; mKIAA1429; MSTP054; VIRMA

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UniProt ID: (Mouse) A2AIV2, (Human) Q69YN4

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Entrez Gene ID: (Mouse) 66185, (Human) 25962, (Rat) 313061

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Function(s)

poly(A) RNA binding

Process(es)

mRNA processing RNA splicing mRNA methylation

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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KIAA1429 Polyclonal Antibody

KIAA1429 Antibody (PA5-95717) in IHC (P)

Product Details

PA5-95717

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

RNA Immunoprecipitation (RIP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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