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KV3.3 (KCNC3) Antibody (PA5-115449) in ICC/IF
Immunocytochemistry analysis of KV3.3 (KCNC3) in HepG2 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115449) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated g... View More
Product Details
PA5-115449
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human KCNC3(Accession Q14003), corresponding to amino acid residues A671-I721.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2900085
Product Specific Information
Antibody detects endogenous levels of total KCNC3.
Target Information
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: KSHIIID; potassium channel, voltage gated Shaw related subfamily C, member 3; potassium voltage gated channel, Shaw-related subfamily, member 3; Potassium voltage-gated channel subfamily C member 3; potassium voltage-gated channel, Shaw-related subfamily, member 3; Shaw-related voltage-gated potassium channel protein 3; Voltage-gated potassium channel KCNC3; voltage-gated potassium channel protein KV3.3; Voltage-gated potassium channel subunit Kv3.3
Gene Aliases: KCNC3; Kcr2-3; KSHIIID; KV3.3; SCA13
UniProt ID: (Human) Q14003, (Mouse) Q63959
Entrez Gene ID: (Human) 3748, (Mouse) 16504, (Rat) 117101
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