Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
Peptide sequence: YPNSIQEYIR QLPPNFPYRD DVMSVNPTCL VLIILLFISI ILTFKGYLIS
Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
LAPTM4B is a multi-pass membrane protein. It belongs to the LAPTM4/LAPTM5 transporter family. LAPTM4b has active role in disease progression of malignant cells and is involved in cell proliferation and multidrug resistance. The genetic polymorphism of LAPTM4B is a potential risk factor for the development of colon cancer and gastric cancer. The research results also indicated that LAPTM4B may be a clinically useful prognostic indicator for ovarian carcinoma and may play a role in human hepatocellular carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: lysosomal associated protein transmembrane 4 beta; Lysosomal-associated transmembrane protein 4B; Lysosome-associated transmembrane protein 4-beta
Gene Aliases: LAPTM4B; LAPTM4beta; LC27; PSEC0001
UniProt ID: (Human) Q86VI4
Entrez Gene ID: (Human) 55353
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