Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 1
LAX1 Antibody (PA5-88428) in WB
Western blot analysis of LAX1 in extracts of various cell lines. Samples were incubated with LAX1 Polyclonal antibody (Product # PA5-88428) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Product Details
PA5-88428
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 77-398 of human LAX1 (NP_0602432)
Conjugate
Form
Liquid
Concentration
0.39 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2804905
Product Specific Information
Immunogen sequence: MPLLTLPQTR QRAKNIYDIL PWRQEDLGRH ESRSMRIFST ESLLSRNSES PEHVPSQAGN AFQEHTAHIH ATEYAVGIYD NAMVPQMCGN LTPSAHCINV RASRDCASIS SEDSHDYVNV PTAEEIAETL ASTKSPSRNL FVLPSTQKLE FTEERDEGCG DAGDCTSLYS PGAEDSDSLS NGEGSSQISN DYVNMTGLDL SAIQERQLWV AFQCCRDYEN VPAADPSGSQ QQAEKDVPSS NIGHVEDKTD DPGTHVQCVK RTFLASGDYA DFQPFTQSED SQMKHREEMS NEDSSDYENV LTAKLGGRDS EQGPGTQLLP DE; Positive Samples: Raji, Mouse liver; Cellular Location: Cell membrane, Single-pass type III membrane protein
Target Information
Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: LAT-like membrane associated protein; Linker for activation of X cells; Lymphocyte transmembrane adapter 1; Membrane-associated adapter protein LAX
Gene Aliases: A530029E09; E430019B13Rik; LAX; LAX1
UniProt ID: (Human) Q8IWV1, (Mouse) Q8BHB3
Entrez Gene ID: (Human) 54900, (Mouse) 240754
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support