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This antibody detects recombinant human LHX5 in direct ELISAs and Western blots. In direct ELISAs, approximately 20% cross-reactivity with recombinant human (rh) LIM1 is observed, and less than 5% cross-reactivity with rhLHX2, and rhLHX9 is observed.
Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in the control of differentiation and development of the forebrain. In mice, this protein is essential for the regulation of precursor cell proliferation and the control of neuronal differentiation and migration during hippocampal development. This protein is involved in learning and motor functions in adult mice.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Homeobox protein LIM-2; LIM homeo box protein 5; LIM homeobox protein 5; LIM/homeobox protein Lhx5; MGC129689
Gene Aliases: LHX5; Lim-2; Lim2
UniProt ID: (Human) Q9H2C1, (Mouse) P61375, (Rat) P61376
Entrez Gene ID: (Human) 64211, (Mouse) 16873, (Rat) 124451
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