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Product Details
BS-11872R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human LIN7C, amino acids 86-197.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Protein assembly at the post synaptic density (PSD) of neuronal synapses is mediated in part by protein interactions with PDZ (PSD-95/discs large/zona occludens-1) motifs. The Mammalian LIN-7 (MALS) proteins are a family of small synaptic proteins that are the mammalian homologs of LIN-7, a C. elegans protein essential for vulval development. MALS proteins are also known as Veli (Vertebrate Lin-7) proteins. MALS-3 mRNA is most abundant in kidney, followed by brain, liver, thymus and heart. MALS-3 is undetectable in spleen. In cultured cortical neurons, MALS proteins are clustered together with PSD-95 and NMDA-type glutamate receptors. MALS proteins are suggested to have roles in regulating the recruitment of neurotransmitter receptors to the PSD and in the assembly of proteins involved in synaptic vesicle exocytosis and synaptic junctions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ11215; lin 7 homolog C; lin-7 homolog C; LIN-7 protein 3; lin-7-C; Lin-7C; MALS-3; Mammalian lin-seven protein 3; mLin7C; Protein lin-7 homolog C; Veli-3; veli-3 protein; vertebrate homolog of C. elegans Lin-7 type 3; Vertebrate lin-7 homolog 3
Gene Aliases: 9130007B12Rik; AI303698; AU019331; AW125731; D2Ertd520e; LIN-7-C; LIN-7C; LIN7C; MALS-3; MALS3; VELI3
UniProt ID: (Human) Q9NUP9, (Rat) Q792I0, (Mouse) O88952
Entrez Gene ID: (Human) 55327, (Rat) 60442, (Mouse) 22343
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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