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LITAF Antibody (PA5-96333) in IHC (P)
Immunohistochemistry analysis of LITAF in paraffin-embedded human prostate. Samples were incubated with LITAF Polyclonal antibody (Product # PA5-96333) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-96333
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-161 of human LITAF (NP_0048532)
Conjugate
Form
Liquid
Concentration
0.86 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2808135
Product Specific Information
Immunogen sequence: MSVPGPYQAA TGPSSAPSAP PSYEETVAVN SYYPTPPAPM PGPTTGLVTG PDGKGMNPPS YYTQPAPIPN NNPITVQTVY VQHPITFLDR PIQMCCPSCN KMIVSQLSYN AGALTWLSCG SLCLLGCIAG CCFIPFCVDA LQDVDHYCPN CRALLGTYKR L; Positive Samples: K-562, HeLa, HepG2, BT-474; Cellular Location: Cytoplasmic side, Lysosome membrane, Peripheral membrane protein
Target Information
Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CMT1C; Estrogen-enhanced transcript protein; FLJ38636; lipopolysaccharide-induced TNF factor; lipopolysaccharide-induced TNF-alpha factor; Lipopolysaccharide-induced tumor necrosis factor-alpha factor; Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog; LITAF-like protein; LPS-induced TNF-alpha factor; LPS-induced TNF-alpha factor homolog; mEET; MGC116698; MGC116700; MGC116701; MGC125274; MGC125275; MGC125276; NEDD4 WW domain-binding protein 3; p53-induced gene 7 protein; PIG 7; Small integral membrane protein of lysosome/late endosome; tumor protein p53 inducible protein 7
Gene Aliases: 3222402J11Rik; C85531; LITAF; N4WBP3; PIG7; SIMPLE; TBX1; TP53I7
UniProt ID: (Human) Q99732, (Mouse) Q9JLJ0
Entrez Gene ID: (Human) 9516, (Mouse) 56722
regulation of cytokine production
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
apoptotic process
signal transduction
aging
negative regulation of NF-kappaB import into nucleus
positive regulation of I-kappaB kinase/NF-kappaB signaling
cellular response to lipopolysaccharide
regulation of transcription, DNA-templated
response to lipopolysaccharide
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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