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Invitrogen
Laminin-211 Recombinant Rabbit Monoclonal Antibody (19H2L5)
FIGURE: 1 / 1
Laminin-211 Antibody (702201) in ICC/IF
For immunofluorescence analysis, C2C12 cells were fixed and permeabilized for detection of endogenous Laminin211 using Anti-Laminin211 Recombinant Rabbit Monoclonal Antibody (Product # 702201, 2 µg/mL) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000). Panel a) shows representative cells that were stained for detection ... View More
Product Details
702201
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
19H2L5
Immunogen
Protein corresponding to Human LAMA2 (aa 1170-1380)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.2
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2633067
Product Specific Information
This antibody is predicted to react with Monkey, Rabbit, Cat and Bovine
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
Laminin is a non-collagenous protein of basement membranes. By rotary shadowing it has a cross-like shape, consisting of one long arm, (400 kD) and three short arms (200 kD). Antibodies to laminin localize exclusively in basement membranes. Laminin is found throughout the basement membrane, but the reaction with the antibodies to laminin is more intense in the lamina lucida, the part of the basement membrane adjacent to the cell membrane. Laminin binds to type IV collagen, a component exclusively localized in the basement membrane. Laminin has been shown to play a role in cell adhesion and attachment in vivo and in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dystrophia muscularis; laminin alpha-2; laminin M; Laminin M chain; Laminin subunit alpha-2; laminin, alpha 2; Laminin-12 subunit alpha; Laminin-2 subunit alpha; Laminin-4 subunit alpha; Merosin heavy chain
Gene Aliases: 5830440B04; dy; LAMA2; LAMM; mer; merosin; mKIAA4087
UniProt ID: (Human) P24043, (Mouse) Q60675
Entrez Gene ID: (Human) 3908, (Mouse) 16773
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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