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Product Details
PA5-22903
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Hamster,
Human,
Invertebrate,
Mammal,
Mouse,
Sheep,
Rabbit,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Laminin isolated from mouse EHS tumor.
Conjugate
Excitation/Emission Max
556/570 nm
View spectra
Form
Liquid
Concentration
0.99 mg/mL
Purification
IgG fraction
Storage buffer
50mM sodium borate
Contains
0.05% sodium azide
Storage conditions
4° C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11157672
Product Specific Information
This antibody is pan-specific and reacts well with all Laminin isoforms tested: Laminin-1 (alpha-1, beta-1, and gamma-1) and Laminin-2 (alpha-2, beta-1, and gamma-1).
The antibody functionally inhibits Laminin in mouse and rat. It binds to Laminin and inhibits most, if not all, of its cell adhesion and growth promotive properties. Immunostaining is enhanced by antigen retrieval with pepsin, especially paraffin tissue. Suggested positive control: basement membranes (blood vessels of any tissue, tumors, nerve).
Target Information
Laminin antibodies are widely used to label blood vessels and basement membranes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dystrophia muscularis; Laminin A chain; laminin alpha 2 subunit; laminin B1; Laminin B1 chain; laminin B1 subunit 1; Laminin B2 chain; Laminin M chain; Laminin subunit alpha-1; Laminin subunit alpha-2; Laminin subunit beta-1; Laminin subunit gamma-1; laminin, alpha 1; laminin, alpha 2; laminin, beta 1; laminin, gamma 1 (formerly LAMB2); laminin-1; Laminin-1 subunit alpha; Laminin-1 subunit beta; Laminin-1 subunit gamma; Laminin-10 subunit beta; Laminin-10 subunit gamma; Laminin-11 subunit gamma; Laminin-12 subunit alpha; Laminin-12 subunit beta; Laminin-2 subunit alpha; Laminin-2 subunit beta; Laminin-2 subunit gamma; Laminin-3 subunit alpha; Laminin-3 subunit gamma; Laminin-4 subunit alpha; Laminin-4 subunit gamma; Laminin-6 subunit beta; Laminin-6 subunit gamma; Laminin-7 subunit gamma; Laminin-8 subunit beta; Laminin-8 subunit gamma; Laminin-9 subunit gamma; Merosin heavy chain; S-LAM alpha; S-LAM gamma; S-laminin subunit alpha; S-laminin subunit gamma
Gene Aliases: 5830440B04; AA408497; B2e; C77966; C80098; C81607; CLM; D130003D08Rik; dy; I79_015129; I79_017505; LAMA; Lama-1; LAMA1; LAMA2; Lamb-1; LAMB1; Lamb1-1; LAMB2; LAMC1; LAMM; LIS5; mer; merosin; mKIAA4087; PTBHS; S-LAM-alpha
UniProt ID: (Human) P25391, (Human) P24043, (Human) P07942, (Human) P11047, (Mouse) P19137, (Mouse) Q60675, (Mouse) P02469
Entrez Gene ID: (Human) 284217, (Sheep) 101102692, (Rabbit) 100357482, (Rabbit) 100350500, (Human) 3908, (Sheep) 101117424, (Human) 3912, (Sheep) 101105743, (Rabbit) 100358679, (Human) 3915, (Rabbit) 103346447, (Sheep) 101105588, (Chinese hamster) 100765555, (Mouse) 16772, (Rat) 316758, (Rat) 309368, (Mouse) 16773, (Mouse) 16777, (Rat) 298941, (Chinese hamster) 100757343, (Rat) 117036, (Chinese hamster) 100761564, (Mouse) 226519
cell adhesion
cell surface receptor signaling pathway
regulation of cell adhesion
extracellular matrix organization
regulation of cell migration
regulation of embryonic development
axon guidance
muscle organ development
myelination in peripheral nervous system
positive regulation of synaptic transmission, cholinergic
neuronal-glial interaction involved in cerebral cortex radial glia guided migration
positive regulation of cell migration
neuron projection development
substrate adhesion-dependent cell spreading
endodermal cell differentiation
odontogenesis
positive regulation of epithelial cell proliferation
protein complex assembly
endoderm development
cell migration
extracellular matrix disassembly
hemidesmosome assembly
morphogenesis of an epithelial sheet
tissue development
establishment of epithelial cell apical/basal polarity
retina development in camera-type eye
epithelial tube branching involved in lung morphogenesis
branching involved in salivary gland morphogenesis
retinal blood vessel morphogenesis
biological_process
negative regulation of cell adhesion
embryo implantation
learning or memory
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