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Invitrogen
Laminin gamma-1,2,3 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 7
Laminin gamma-1,2,3 Antibody (PA5-79576) in IHC (P)
Immunohistochemistry analysis of Laminin on paraffin-embedded rat cardiac muscle tissue. Antigen retrieval was performed using citrate buffer (pH6, epitope retrieval solution) for 20 mins. Sample was blocked using 10% goat serum, incubated with Laminin polyclonal antibody (Product# PA5-79576) with a dilution of 1 µg/mL (overnight at 4°C), and followed by biotinylated goat anti-rabbit IgG (30 minutes at 37°C... View More
Product Details
PA5-79576
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide mixture of laminin gamma1,2,3(NKLNEIEGSLNKAKDEMKAS; DLEERVRRQRNHLHLLETSI; LQLDSHGALHHKLRQLEEES)
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2746691
Product Specific Information
This antibody reacts will all 3 isoforms of Laminin gamma: Laminin gamma-1, gamma-2 and gamma-3.
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Extracellular matrix (ECM) surrounds and separates most tissue compartments, determines tissue architecture and dynamically interacts with its surrounding cells. The basement membrane is a part of the ECM and is composed of collagens, proteoglycans, elastin and several glycoproteins of which laminin is the most abundant. Laminins are large heterotrimeric, noncollagenous glycoproteins composed of alpha, beta, and gamma chains Dystroglycan is a major laminin receptor in muscle and epithelia, and nidogen is a high-affinity laminin-binding protein important for basement-membrane assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alternatively spliced laminin gamma2 chain; BM600-100kDa; Cell-scattering factor 140 kDa subunit; CSF 140 kDa subunit; Epiligrin subunit gamma; Kalinin subunit gamma; Kalinin/nicein/epiligrin 100 kDa subunit; Ladsin 140 kDa subunit; lamimin, gamma 2; Laminin B2 chain; Laminin B2t chain; laminin gamma2 chain; Laminin subunit gamma-1; Laminin subunit gamma-2; Laminin subunit gamma-3; laminin, gamma 1 (formerly LAMB2); laminin, gamma 2; laminin, gamma 3; Laminin-1 subunit gamma; Laminin-10 subunit gamma; Laminin-11 subunit gamma; Laminin-12 subunit gamma; Laminin-14 subunit gamma; Laminin-15 subunit gamma; Laminin-2 subunit gamma; Laminin-3 subunit gamma; Laminin-4 subunit gamma; Laminin-5 subunit gamma; Laminin-6 subunit gamma; Laminin-7 subunit gamma; Laminin-8 subunit gamma; Laminin-9 subunit gamma; Large adhesive scatter factor 140 kDa subunit; Nicein subunit gamma; nicein, 100kD; nicein, 100kDa; S-LAM gamma; S-laminin subunit gamma
Gene Aliases: AA589349; AI562206; AW240805; B2e; B2T; BM600; CSF; EBR2; EBR2A; LAMB2; LAMB2T; LAMC1; LAMC2; LAMC3; LAMNB2; OCCM
UniProt ID: (Human) P11047, (Human) Q13753, (Human) Q9Y6N6, (Mouse) Q9R0B6
Entrez Gene ID: (Human) 3915, (Human) 3918, (Human) 10319, (Mouse) 226519, (Rat) 117036, (Mouse) 16782, (Rat) 192362, (Rat) 311862, (Mouse) 23928
protein complex assembly
cell adhesion
endoderm development
cell migration
extracellular matrix disassembly
extracellular matrix organization
hemidesmosome assembly
substrate adhesion-dependent cell spreading
positive regulation of epithelial cell proliferation
epidermis development
cell morphogenesis involved in differentiation
visual perception
astrocyte development
retina development in camera-type eye
neuron projection development
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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