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M6PR Antibody (CF812721) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY M6PR (RC201277, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-M6PR. (1. Positive lysates LY419372 (100 µg) and LC419372 (20 µg) can be purchased separately from OriGene.
Product Details
CF812721
Product Specifications
Species Reactivity
Dog,
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI2F3
Immunogen
Human recombinant protein fragment corresponding to amino acids 27-185 of human M6PR produced in E.coli.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
M6PR is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 46 kDa mannose 6-phosphate receptor; 46-kDa mannose 6-phosphate receptor; Cation-dependent mannose-6-phosphate receptor; CD Man-6-P receptor; CD-MPR; FLJ32994; mannose-6-phosphate receptor (cation dependent); MPR 46; Mr 46,000 Man6PR; small mannose 6-phosphate receptor
Gene Aliases: 46mpr; CD-M6PR; CD-MPR; M6PR; MPR 46; MPR-46; MPR46; MPRD; SMPR
UniProt ID: (Human) P20645, (Mouse) P24668, (Rat) Q6AY20
Entrez Gene ID: (Human) 4074, (Dog) 477700, (Mouse) 17113, (Rat) 312689
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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