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Invitrogen
MAG Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 6
MAG Antibody (PA5-30087) in IHC (P)
MAG Polyclonal Antibody detects MAG protein at on rat fore brain by immunohistochemical analysis. Sample: Paraffin-embedded rat fore brain. MAG Polyclonal Antibody (Product # PA5-30087) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Product Details
PA5-30087
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 29 and 356 of Human MAG
Conjugate
Form
Liquid
Concentration
0.61 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2547561
Product Specific Information
Recommended positive controls: human brain, mouse brain, rat brain.
Predicted reactivity: Mouse (95%), Rat (95%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 1B236; Brain neuron cytoplasmic protein 3; Myelin-associated glycoprotein; S-MAG (C-term.); sialic acid binding Ig-like lectin 4A; Sialic acid-binding Ig-like lectin 4a; sialic acid-binding immunoglobulin-like lectin 4A; Siglec-4a
Gene Aliases: GMA; MAG; S-MAG; SIGLEC-4A; SIGLEC4A; SPG75
UniProt ID: (Human) P20916, (Rat) P07722, (Mouse) P20917
Entrez Gene ID: (Human) 4099, (Rat) 29409, (Mouse) 17136
cell adhesion
positive regulation of myelination
positive regulation of astrocyte differentiation
negative regulation of axonogenesis
leukocyte migration
cellular response to mechanical stimulus
nervous system development
negative regulation of neuron projection development
substantia nigra development
negative regulation of neuron differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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