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Product Details
BS-18635R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human MAK, amino acids 101-200.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dJ417M14.2; Male germ cell-associated kinase; male germ cell-associated kinase retinal-enriched isoform; Protein kinase RCK; serine/threonine protein kinase MAK; Serine/threonine-protein kinase MAK; testicular secretory protein Li 28
Gene Aliases: A930010O05Rik; MAK; Rck; RP62
UniProt ID: (Human) P20794, (Mouse) Q04859, (Rat) P20793
Entrez Gene ID: (Human) 4117, (Mouse) 17152, (Rat) 25677
transcription coactivator activity
protein kinase activity
cyclin-dependent protein serine/threonine kinase activity
protein binding
ATP binding
nucleotide binding
protein serine/threonine kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
multicellular organism development
spermatogenesis
cell differentiation
photoreceptor cell maintenance
protein autophosphorylation
regulation of cell cycle
phosphorylation
regulation of nucleic acid-templated transcription
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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