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FIGURE: 1 / 2
MAK Antibody (H00004117-D01P) in WB
Western Blot analysis of MAK expression in transfected 293T cell line (H00004117-T01) by MAK MaxPab polyclonal antibody.
Lane 1: MAK transfected lysate(52.60 KDa).
Lane 2: Non-transfected lysate.
Lane 1: MAK transfected lysate(52.60 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00004117-D01P
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MAK (AAH39825.1, 1 a.a. approximately 457 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MNRYTTMRQL GDGTYGSVLM GKSNESGELV AIKRMKRKFY SWDECMNLRE VKSLKKLNHA NVIKLKEVIR ENDHLYFIFE YMKENLYQLM KDRNKLFPES VIRNIMYQIL QGLAFIHKHG FFHRDMKPEN LLCMGPELVK IADFGLAREL RSQPPYTDYV STRWYRAPEV LLRSSVYSSP IDVWAVGSIM AELYMLRPLF PGTSEVDEIF KICQVLGTPK KSDWPEGYQL ASSMNFRFPQ CVPINLKTLI PNASNEAIQL MTEMLNWDPK KRPTASQALK HPYFQVGQVL GPSSNHLESK QSLNKQLQPL ESKPSLVEVE PKPLPDIIDQ VVGQPQPKTS QQPLQPIQPP QNLSVQQPPK QQSQEKPPQT LFPSIVKNMP TKPNGTLSHK SGRRRWGQTI FKSGDSWEEL EDYDFGASHS KKPSMGVFKE KRKKDSPFRQ QVKMAVISLS AHQFPTL
Target Information
The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dJ417M14.2; Male germ cell-associated kinase; male germ cell-associated kinase retinal-enriched isoform; Protein kinase RCK; serine/threonine protein kinase MAK; Serine/threonine-protein kinase MAK; testicular secretory protein Li 28
Gene Aliases: A930010O05Rik; MAK; Rck; RP62
UniProt ID: (Human) P20794, (Mouse) Q04859
Entrez Gene ID: (Human) 4117, (Mouse) 17152
transcription coactivator activity
protein kinase activity
cyclin-dependent protein serine/threonine kinase activity
protein binding
ATP binding
nucleotide binding
protein serine/threonine kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
multicellular organism development
spermatogenesis
cell differentiation
photoreceptor cell maintenance
protein autophosphorylation
regulation of cell cycle
phosphorylation
regulation of nucleic acid-templated transcription
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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