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Product Details
39395
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG
Class
Monoclonal
Type
Antibody
Immunogen
This MALT1 antibody was raised against a recombinant protein corresponding to amino acids 701-808 of mouse MALT1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
70mM tris, pH 8, with 31mM glycine, 0.07mM EDTA, 30% glycerol, 105mM NaCl
Contains
0.035% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2793240
Target Information
MALT1/Paracaspase (MALT1) was independently identified as a member of the human paracaspase family and an interacting partner of B-cell lymphoma (Uren et al., 2000). MALT1 is a caspase-like protein that contains an N-terminal death domain, two Ig-like domains, and a C-terminal caspase-like domain. It binds to Bcl10 through its Ig-like domains and cooperates with Bcl10 to activate NF-kappaB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: caspase-like protein; DKFZp434L132; MALT lymphoma-associated translocation; malt-1; malt1; MALT1 protease; mucosa associated lymphoid tissue lymphoma translocation gene 1; Mucosa-associated lymphoid tissue lymphoma translocation protein 1; Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog; Paracaspase; paracaspase 1; paracaspase-1
Gene Aliases: A630046N12; D430033E09Rik; IMD12; MALT1; MLT; MLT1; PCASP1
UniProt ID: (Human) Q9UDY8, (Mouse) Q2TBA3
Entrez Gene ID: (Human) 10892, (Mouse) 240354
B-1 B cell differentiation
stimulatory C-type lectin receptor signaling pathway
response to molecule of bacterial origin
positive regulation of T cell cytokine production
proteolysis
defense response
activation of NF-kappaB-inducing kinase activity
response to fungus
protein ubiquitination
positive regulation of protein ubiquitination
positive regulation of interleukin-2 production
Fc-epsilon receptor signaling pathway
T cell proliferation
regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
T cell receptor signaling pathway
regulation of T cell receptor signaling pathway
positive regulation of T cell activation
positive regulation of NF-kappaB transcription factor activity
nuclear export
protein oligomerization
apoptotic process
I-kappaB kinase/NF-kappaB signaling
B cell activation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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