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Product Details
PA5-28107
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a region within amino acids 1 and 45 of Human MAML1
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2545583
Product Specific Information
Recommended positive controls: HeLa, HeLa nucleus, mouse heart.
Predicted reactivity: Mouse (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ53540; Mam-1; MAML1; mastermind homolog; mastermind-like 1; Mastermind-like protein 1; mastermind-like transcriptional coactivator 1
Gene Aliases: AI644666; AW743257; D930008C07Rik; KIAA0200; Mam-1; Mam1; MAML1; mKIAA0200
UniProt ID: (Human) Q92585, (Mouse) Q6T264
Entrez Gene ID: (Human) 9794, (Mouse) 103806
atrioventricular node development
transcription initiation from RNA polymerase II promoter
protein phosphorylation
Notch signaling pathway
positive regulation of transcription of Notch receptor target
positive regulation of myotube differentiation
myoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
atrioventricular node cell development
transcription, DNA-templated
regulation of transcription, DNA-templated
positive regulation of muscle cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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