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Product Details
PA5-72734
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
LEMD3 antibody for an 18 amino acid synthetic peptide near the carboxy terminus of human LEMD3. The immunogen is within the last 50 amino acids of LEMD3.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2718588
Target Information
Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced cell proliferation arrest.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Inner nuclear membrane protein Man1; integral inner nuclear membrane protein; integral inner nuclear membrane protein MAN1; LEM domain-containing protein 3
Gene Aliases: AI316861; LEMD3; MAN1
UniProt ID: (Human) Q9Y2U8, (Mouse) Q9WU40
Entrez Gene ID: (Human) 23592, (Mouse) 380664
negative regulation of transforming growth factor beta receptor signaling pathway
negative regulation of BMP signaling pathway
negative regulation of activin receptor signaling pathway
angiogenesis
blood vessel endothelial cell migration involved in intussusceptive angiogenesis
nucleus organization
skeletal muscle cell differentiation
regulation of cell cycle
regulation of extracellular matrix organization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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