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NEUROD6 contains 1 basic helix-loop-helix (bHLH) domain. It activates E box-dependent transcription in collaboration with TCF3/E47 and may be a trans-acting factor involved in the development and maintenance of the mammalian nervous system. It transactivates the promoter of its own gene.
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Protein Aliases: atonal homolog 2; bHLHa2; brain my051 protein; Class A basic helix-loop-helix protein 2; Helix-loop-helix protein mATH-2; mATH2; NeuroD6; neurogenic differentiation 6; Neurogenic differentiation factor 6; Protein atonal homolog 2; Protein NEX-1
Gene Aliases: Ath2; ATOH2; BHLHA2; Math-2; MATH2; My051; NEUROD6; Nex; Nex1; NEX1M; RGD1562793
UniProt ID: (Human) Q96NK8, (Mouse) P48986
Entrez Gene ID: (Human) 63974, (Mouse) 11922, (Rat) 500137
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