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MATK Antibody (PA5-93126) in IHC (P)
Immunohistochemistry analysis of MATK in paraffin-embedded mouse kidney. Samples were incubated with MATK Polyclonal antibody (Product # PA5-93126) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-93126
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 352-466 of human MATK (NP_6476111)
Conjugate
Form
Liquid
Concentration
1.29 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2806633
Product Specific Information
Immunogen sequence: PEALKHGKFT SKSDVWSFGV LLWEVFSYGR APYPKMSLKE VSEAVEKGYR MEPPEGCPGP VHVLMSSCWE AEPARRPPFR KLAEKLAREL RSAGAPASVS GQDADGSTSP RSQEP; Positive Samples: THP-1; Cellular Location: Cytoplasm, Membrane
Target Information
MATK (Hyl) is a non-receptor CSK-type protein tyrosine kinase that is thought to function in signal transduction pathways important in megakaryocyte growth and/or differentiation. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CHK; CSK homologous kinase; Csk-homologous kinase; Csk-type protein tyrosine kinase; DKFZp434N1212; Hematopoietic consensus tyrosine-lacking kinase; hydroxyaryl-protein kinase; HYL tyrosine kinase; leukocyte carboxyl-terminal src kinase related; megakaryocyte-associated tyrosine kinase (non-receptor protein tyrosine kinase); Megakaryocyte-associated tyrosine-protein kinase; MGC1708; MGC2101; non-receptor protein kinase protein; Protein kinase BATK; Protein kinase HYL; Protein kinase NTK; tyrosine kinase MATK; Tyrosine-protein kinase CTK; tyrosylprotein kinase
Gene Aliases: Batk; CHK; CTK; HHYLTK; HYL; HYLTK; Lsk; MATK; Ntk
UniProt ID: (Human) P42679, (Mouse) P41242, (Rat) P41243
Entrez Gene ID: (Human) 4145, (Mouse) 17179, (Rat) 60450
morphogenesis of an epithelium
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
phosphorylation
cell migration
cell differentiation
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
innate immune response
mesoderm development
cell proliferation
positive regulation of cell proliferation
ERBB2 signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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