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MCMBP Antibody (PA5-78583) in WB
C10orf119 antibody detects C10orf119 protein by western blot analysis. Various whole cell extracts (30 µg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with C10orf119 antibody MCMBP Polyclonal Antibody (Product # PA5-78583) diluted by 1:1,000.
Product Details
PA5-78583
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human MCMBP. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
2.74 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 0.1M glycine, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2736128
Product Specific Information
Positive Control: 293T, A431
Predicted Reactivity: Mouse (96%), Rat (95%), Dog (97%), Pig (100%), Chicken (90%), Rhesus Monkey (100%), Bovine (99%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
MEK1 (Mitogen activated protein kinase kinase 1) catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. MEK1 activates ERK1 and ERK2 MAP kinases. Mitogen activated protein kinase kinase 2 (MEK2 or MAPKK2) is a member of a family of tyrosine/threonine protein kinases that activate the ERK1 and 2 and MAPK enzymes by phosphorylating both residues within the threonine/glutamate/tyrosine (TEY) motif in the activation loop. MEK1 and 2 are also activated by dual phosphorylation, which occurs on serine 218 and 222, in the activation loop of the MEK. Threonine 292 of MEK1 is phosphorylated by ERK 2, which serves as a negative feedback loop by suppressing activation of MEK1.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cj119; MCM-binding protein; MCM-BP; Mini-chromosome maintenance complex-binding protein; minichromosome maintenance complex-binding protein
Gene Aliases: C10orf119; MCM-BP; MCMBP
UniProt ID: (Human) Q9BTE3
Entrez Gene ID: (Human) 79892
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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