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MEOX2 Antibody (H00004223-D01P) in WB
Western Blot analysis of MEOX2 expression in transfected 293T cell line (H00004223-T01) by MEOX2 MaxPab polyclonal antibody.
Lane 1: MEOX2 transfected lysate(33.50 KDa).
Lane 2: Non-transfected lysate.
Lane 1: MEOX2 transfected lysate(33.50 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00004223-D01P
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MEOX2 (AAH17021.1, 1 a.a. approximately 303 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MEHPLFGCLR SPHATAQGLH PFSQSSLALH GRSDHMSYPE LSTSSSSCII AGYPNEEGMF ASQHHRGHHH HHHHHHHHHQ QQQHQALQTN WHLPQMSSPP SAARHSLCLQ PDSGGPPELG SSPPVLCSNS SSLGSSTPTG AACAPGDYGR QALSPAEAEK RSGGKRKSDS SDSQEGNYKS EVNSKPRKER TAFTKEQIRE LEAEFAHHNY LTRLRRYEIA VNLDLTERQV KVWFQNRRMK WKRVKGGQQG AAAREKELVN VKKGTLLPSE LSGIGAATLQ QTGDSIANED SHDSDHSSEH AHL
Target Information
Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Growth arrest-specific homeobox; Homeobox protein MOX-2; mesenchyme homeo box 2 (growth arrest-specific homeo box); Mesenchyme homeobox 2
Gene Aliases: GAX; MEOX2; Mox-2; MOX2
UniProt ID: (Human) P50222, (Rat) P39020
Entrez Gene ID: (Human) 4223, (Rat) 29279
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
homeodomain transcription factor
angiogenesis
somite specification
transcription from RNA polymerase II promoter
multicellular organism development
skeletal muscle tissue development
blood circulation
positive regulation of transcription from RNA polymerase II promoter
palate development
limb development
neuron death
negative regulation of cell migration involved in sprouting angiogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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