Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 4
MRP2 Antibody (BS-1092R) in IHC (P)
Formalin-fixed and paraffin-embedded human liver carcinoma labeled with Anti-MRP2 Polyclonal Antibody, Unconjugated(bs-1092R) 1:200, overnight at 4°C, The secondary antibody was Goat Anti-Rabbit IgG,PE conjugated(bs-0295G-PE)used at 1:200 dilution for 40 minutes at 37°C.
Product Details
BS-1092R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human MRP2, amino acids 485-615.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: ATP-binding cassette sub-family C member 2; ATP-binding cassette, sub-family C (CFTR/MRP), member 2; calicular multispecific organic anion transporter; Canalicular multidrug resistance protein; Canalicular multispecific organic anion transporter 1; Human MRP2; KIAA1010; multidrug resistance associated protein 2; multidrug resistance protein 2; Multidrug resistance-associated protein 2
Gene Aliases: ABC30; ABCC2; AI173996; CMOAT; CMOAT1; CMRP; DJS; MRP2
UniProt ID: (Human) Q92887, (Rat) Q63120, (Mouse) Q8VI47
Entrez Gene ID: (Human) 1244, (Rat) 25303, (Mouse) 12780
protein binding
ATP binding
organic anion transmembrane transporter activity
bilirubin transmembrane transporter activity
protein domain specific binding
ATPase activity, coupled to transmembrane movement of substances
anion transmembrane-transporting ATPase activity
ATP-binding cassette (ABC) transporter
transport
drug transmembrane transport
response to oxidative stress
response to heat
bilirubin transport
prostaglandin transport
cellular chloride ion homeostasis
response to methotrexate
response to estrogen
response to arsenic-containing substance
response to steroid hormone
transmembrane transport
thyroid hormone transport
anion transmembrane transport
metabolic process
organic anion transport
response to drug
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support