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Product Details
MA5-24417
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
2G4
Immunogen
OGN (NP_148935.1, 200 a.a. ~ 298 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2633389
Product Specific Information
Peptide Sequence: KSRGIKANAF KKLNNLTFLY LDHNALESVP LNLPESLRVI HLQFNNIASI TDDTFCKAND TSYIRDRIEE IRLEGNPIVL GKHPNSFICL KRLPIGSYF
Target Information
Mimecan induces ectopic bone formation in conjunction with transforming growth factor beta. Mimecan is a small proteoglycan which contains tandem leucine-rich repeats. Mimecan is encoded by the OGN gene, a member of the small leucine-rich proteoglycan (SLRP) family of proteins. Mimecan induces ectopic bone formation in conjunction with transforming growth factor beta (TGF-beta-1 or TGF-beta-2) and may regulate osteoblast differentiation. High expression of mimecan protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants of mimecan. Alternatively spliced transcript variants that encode mimecan have been found.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: corneal keratan sulfate proteoglycan; Mimecan; mimecan proteoglycan; OIF; Osteoglycin; Osteoinductive factor
Gene Aliases: OG; OGN; OIF; SLRR3A
UniProt ID: (Human) P20774
Entrez Gene ID: (Human) 4969
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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