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Product Details
13879-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mucolipin 3 Fusion Protein Ag4962 (86-285 aa encoded by BC060765)
Conjugate
Form
Liquid
Concentration
0.24 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MVVAFKEEN TIAFKHLFLK GYMDRMDDTY AVYTQSDVYD QLIFAVNQYL QLYNVSVGNH AYENKGTKQS AMAICQHLYK RGNIYPGNDT FDIDPEIETE CFFVEPDEPF HIGTPAENKL NLTLDFHRLL TVELQFKLKA INLQTVRHQE LPDCYDFTLT ITFDNKAHSG RIKISLDNDI SIRECKDWHV SGSIQKNTHY M (86-285 aa encoded by BC060765)
Target Information
Expressed in the cochlea; particularly in the inner and outer hair cells. Defects in Mcoln3 are the cause of the varitin-waddler (Va) phenotype. Classical Va mice exhibit early-onset hearing loss, vestibular defects, pigmentation abnormalities and perinatal lethality. The phenotype varitin-waddler Jackcon (Va-J), which arose in a cross segregating for Va, is similar but less severe. Belongs to the transient receptor family, polycystin subfamily.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: FLJ11006; FLJ36629; MCLN3; Mcoln3 mucolipin 3; MGC124245; MGC124246; MGC71509; Mucolipin-3; Transient receptor potential channel mucolipin 3; TRPML3; varitint-waddler
Gene Aliases: 6720490O21Rik; MCOLN3; TRP-ML3; TRPML3; Va
UniProt ID: (Human) Q8TDD5, (Mouse) Q8R4F0
Entrez Gene ID: (Human) 55283, (Rat) 308022, (Mouse) 171166
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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