Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MAAIYGGVE GGGTRSEVLL VSEDGKILAE ADGLSTNHWL IGTDKCVERI NEMVNRAKRK AGVDPLVPLR SLGLSLSGGD QEDAGRILIE ELRDRFPYLS ESYLITTDAA GSIATATPDG GVVLISGTGS NCRLINPDGS ESGCGGWGHM MGDEGSAYWI AHQAVKIVFD SIDNLEAAPH DIGYVKQAMF HYFQVPDRLG ILTHLYRDFD KCRFAGFCRK IAEGAQQGDP LSRYIFRKAG EMLGRHIVAV LPEIDPVLFQ GKIGLPILCV GSVWKSWELL KEGFLLALTQ GREIQAQNFF SSFTLMKLRH SSALGGASLG ARHIGHLLPM DYSANAIAFY SYTFS (1-344 aa encoded by BC001029)
SPG20 is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GlcNAc kinase; Muramyl dipeptide kinase; N-acetyl-D-glucosamine kinase; N-acetyl-D-mannosamine kinase; N-acetylglucosamine kinase
Gene Aliases: GNK; HSA242910; NAGK
UniProt ID: (Human) Q9UJ70, (Mouse) Q9QZ08, (Rat) P81799
Entrez Gene ID: (Human) 55577, (Mouse) 56174, (Rat) 297393
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