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Immunogen sequence: SGCLELTDSC QPYRSAFYVL EQQRV
NBPF15 (NBPF Member 15), located on 1q21.1, is a Protein Coding gene. This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family contains numerous pseudogenes. Human NBPF15 encodes a 670 AA protein consisting of six clades of Olduvai domains. The entanglements between the mosaic disorder-ordered segments in the NBPF15 N terminus have triggered the multiple types of aggregates and phase transition of NBPF15 proteins, which could be associated with Olduvai-related cognitive dysfunction diseases. Diseases associated with NBPF15 include Neuroblastoma and Hydrolethalus Syndrome 1. An important paralog of this gene is NBPF14.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AB14; NBPF; NBPF Member 15; Neuroblastoma breakpoint family member 15; Neuroblastoma breakpoint family member 16; Neuroblastoma Breakpoint Family, Member 1; neuroblastoma breakpoint family, member 15; Neuroblastoma Breakpoint Family, Member 16
Gene Aliases: AB14; AG3; NBPF15; NBPF16
UniProt ID: (Human) Q8N660
Entrez Gene ID: (Human) 284565
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