Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Antibody detects endogenous levels of total NCOA5.
This gene encodes a coregulator for the alpha and beta estrogen receptors and the orphan nuclear receptor NR1D2. The protein localizes to the nucleus, and is thought to have both coactivator and corepressor functions. Its interaction with nuclear receptors is independent of the AF2 domain on the receptors, which is known to regulate interaction with other coreceptors. Several alternatively spliced transcript variants have been found for this gene.
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Protein Aliases: CIA; Coactivator independent of AF-2; NCoA-5; Nuclear receptor coactivator 5
Gene Aliases: bA465L10.6; CIA; KIAA1637; NCOA5
UniProt ID: (Human) Q9HCD5, (Mouse) Q91W39
Entrez Gene ID: (Human) 57727, (Mouse) 228869, (Rat) 296372
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