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NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene are a cause of mitochondrial complex I deficiency.
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Protein Aliases: hormone-regulated proliferation associated protein 20; hormone-regulated proliferation-associated 20 kDa protein; Hormone-regulated proliferation-associated protein of 20 kDa; Hormone-regulated proliferation-associated protein of 20 kDa homolog; hormone-regulated proliferation-associated protein, 20 kDa; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4; NADH dehydrogenase (ubiquinone) complex I, assembly factor 4; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4; Protein HRPAP20
Gene Aliases: 1110007M04Rik; 3000003G13Rik; AW214064; bA22L21.1; C6orf66; HRPAP20; HSPC125; My013; NDUFAF4
UniProt ID: (Human) Q9P032, (Mouse) Q9D1H6, (Rat) Q9NQR8
Entrez Gene ID: (Human) 29078, (Mouse) 68493, (Rat) 362495
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