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Product Details
PA5-66629
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human NDUFB1. Recombinant protein control fragment (Product #RP-105280).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2662211
Product Specific Information
Immunogen sequence: LDRKSDERLTA FRNKSMLFKR ELQPSEEVTW K
Highest antigen sequence identity to the following orthologs - mouse 36%, rat 39%.
Target Information
NDUFB1 (NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1), also known as CI-MNLL (complex I-MNLL), CI-SGDH or NADH-ubiquinone oxidoreductase MNLL subunit, is a 58 amino acid single-pass membrane protein that localizes to the matrix side of the mitochondrial membrane. A member of the complex I NDUFB1 subunit family, NDUFB1 is encoded by a gene that maps to human chromosome 14q32.12. Chromosome 14 houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder alpha1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CI-MNLL; complex I MNLL subunit; Complex I-MNLL; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1; NADH-ubiquinone oxidoreductase MNLL subunit
Gene Aliases: CI-MNLL; CI-SGDH; MNLL; NDUFB1
UniProt ID: (Human) O75438
Entrez Gene ID: (Human) 4707
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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