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Product Details
PA5-54216
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human NDUFV3. Recombinant protein control fragment (Product #RP-102241).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2644581
Product Specific Information
Immunogen sequence: RVVSKGRGGL RKPEASHSFE NRAPRVTVSA KEKTLLQKPH VDITDPEKPH QPKKKGSPAK PSEGRENARP KTTMPRSQVD EEFLKQSLKE KQLQKTFRLN EIDKESQKPF EVKGPLPVHT KSGLSA
Highest antigen sequence identity to the following orthologs: Mouse - 46%, Rat - 48%.
Target Information
Located in the mitochondrial inner membrane, mitochondrial complex I is the first and largest enzyme in the electron transport chain of oxidative phosphorylation. By oxidizing NADH that is produced in the Krebs cycle, this complex utilizes the two electrons to reduce ubiquinone to ubiquinol, thereby initiating the passage of electrons to successive complexes and ultimately leading to the reduction of oxygen to water. Mitochondrial complex I consists of over 40 subunits and is of considerable clinical interest since defects in any one of the subunits can lead to various myopathies and neuropathies. As a subunit of mitochondrial complex I, NDUFV3 (NADH dehydrogenase [ubiquinone] flavoprotein 3), also designated NADH-ubiquinone oxidoreductase 9 kDa subunit or CI-9kD, is a 108 amino acid protein that is believed to not be involved in catalysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CI-9kD; complex I 10kDa subunit; complex I, mitochondrial respiratory chain, 10-kD subunit; Complex I-9kD; mitochondrial NADH oxidoreductase-like protein; NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa; NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial; NADH-ubiquinone oxidoreductase 9 kD subunit; NADH-ubiquinone oxidoreductase 9 kDa subunit; NADH-ubiquinone oxidoreductase flavoprotein 3, 10kD; Renal carcinoma antigen NY-REN-4
Gene Aliases: CI-10k; CI-9KD; NDUFV3
UniProt ID: (Human) P56181
Entrez Gene ID: (Human) 4731
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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