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NELL1 Antibody (BS-10704R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded Mouse brain; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with NELL1 Polyclonal Antibody, Unconjugated (bs-10704R) at 1:400 overnight at 4°C, DAB staining.
Product Details
BS-10704R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human NELL1, amino acids 201-300.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a cytoplasmic protein that contains epidermal growth factor (EGF)-like repeats. The encoded heterotrimeric protein may be involved in cell growth regulation and differentiation. A similar protein in rodents is involved in craniosynostosis. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: NEL-like protein 1; Nel-related protein 1; neural epidermal growth factor-like 1; Protein kinase C-binding protein NELL1
Gene Aliases: B230343H07Rik; IDH3GL; l7R6; NELL1; NRP1
UniProt ID: (Human) Q92832, (Rat) Q62919, (Mouse) Q2VWQ2
Entrez Gene ID: (Human) 4745, (Rat) 81733, (Mouse) 338352
nervous system development
regulation of gene expression
cell differentiation
positive regulation of bone mineralization
negative regulation of osteoblast proliferation
positive regulation of osteoblast differentiation
negative regulation of cyclin catabolic process
positive regulation of apoptotic process
regulation of osteoblast differentiation
positive regulation of ossification
protein homotrimerization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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