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NR1 Antibody (PA5-55093) in WB
International journal of molecular sciences 2022 -
Expression of post-synaptic proteins in frontal cortex from AOM, and anti-TGF-beta1 mice. ( A , B ) Level of NR1 subunit, PSD-95, GABAR1alpha, and gephyrin in membrane fraction in frontal cortex from mice after TGF-beta1 neutralization and AOM injection with representative immunoblots. Results are the mean +- SEM. n = 6 for NR1 and PSD-95, n = 4 for GABAR1alpha and gephyrin, * p < 0.05 vs. control, one-way ... View More
Product Details
PA5-55093
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human NR1. Recombinant protein control fragment (Product #RP-93089).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2644785
Product Specific Information
Immunogen sequence: QPCSMRHLVS HYLDIASVPR RSFFELLACL SLHELEREKL LEFSSAQGQE ELFEYCNRPR RTILEVLCDF PHTAAAIPPD YLLD
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 88%.
Target Information
This gene encodes an NADPH-dependent diflavin reductase that contains both flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) binding domains. The encoded protein is an enzyme that catalyzes the transfers electrons from NADPH through FAD and FMN cofactors to potential redox partners. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: NADPH-dependent diflavin oxidoreductase 1; NADPH-dependent FMN and FAD-containing oxidoreductase; NDOR1; Novel reductase 1
Gene Aliases: 4930447P04Rik; bA350O14.9; Ndor; NDOR1; NR1
UniProt ID: (Human) Q9UHB4, (Mouse) A2AI05
Entrez Gene ID: (Human) 27158, (Mouse) 78797, (Rat) 311799
NADPH-hemoprotein reductase activity
protein binding
FMN binding
oxidoreductase activity
flavin adenine dinucleotide binding
NADP binding
iron ion binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
epoxide carboxylase activity
reduced coenzyme F420:NADP+ oxidoreductase activity
molecular_function
oxidoreductase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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