Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 2
NTF3 Antibody (H00004908-D01P) in WB
Western Blot analysis of NTF3 expression in transfected 293T cell line (H00004908-T01) by NTF3 MaxPab polyclonal antibody.
Lane 1: NTF3 transfected lysate(29.40 KDa).
Lane 2: Non-transfected lysate.
Lane 1: NTF3 transfected lysate(29.40 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00004908-D01P
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NTF3 (NP_002518.1, 1 a.a. approximately 257 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MSILFYVIFL AYLRGIQGNN MDQRSLPEDS LNSLIIKLIQ ADILKNKLSK QMVDVKENYQ STLPKAEAPR EPERGGPAKS AFQPVIAMDT ELLRQQRRYN SPRVLLSDST PLEPPPLYLM EDYVGSPVVA NRTSRRKRYA EHKSHRGEYS VCDSESLWVT DKSSAIDIRG HQVTVLGEIK TGNSPVKQYF YETRCKEARP VKNGCRGIDD KHWNSQCKTS QTYVRALTSE NNKLVGWRWI RIDTSCVCAL SRKIGRT
Target Information
The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: HDNF; Nerve growth factor 2; Neurotrophic factor; Neurotrophin-3; NGF-2; NT-3
Gene Aliases: AI316846; AI835689; HDNF; NGF-2; NGF2; NT-3; NT3; Ntf-3; NTF3
UniProt ID: (Human) P20783, (Mouse) P20181
Entrez Gene ID: (Human) 4908, (Mouse) 18205
activation of MAPK activity
positive regulation of receptor internalization
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
cell-cell signaling
nervous system development
positive regulation of cell proliferation
positive regulation of cell migration
activation of protein kinase B activity
positive regulation of peptidyl-serine phosphorylation
myelination
regulation of apoptotic process
negative regulation of neuron apoptotic process
regulation of neuron differentiation
positive regulation of glial cell differentiation
neuron projection morphogenesis
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of peptidyl-tyrosine phosphorylation
modulation of synaptic transmission
positive chemotaxis
induction of positive chemotaxis
activation of GTPase activity
positive regulation of actin cytoskeleton reorganization
neuromuscular synaptic transmission
glial cell fate determination
axon guidance
brain development
peripheral nervous system development
epidermis development
nerve development
mechanoreceptor differentiation
regulation of neuron apoptotic process
positive regulation of transcription from RNA polymerase II promoter
enteric nervous system development
neuron development
generation of neurons
smooth muscle cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support