Proteintech

NUB1 Polyclonal Antibody

FIGURE: 1 / 7

NUB1 Antibody (14343-1-AP) in WB

Mouse kidney tissue were subjected to SDS PAGE followed by western blot with 14343-1-AP (NUB1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

NUB1 Antibody in Immunoprecipitation (IP)

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Product Details

14343-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 2 publications 2 publications

Immunohistochemistry (IHC)

Assay-dependent

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

NUB1 Fusion Protein Ag5668 (252-601 aa encoded by BC046354)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.19 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: YGIALPCLL DADKYFCECC RELLDTVDNY AVLQLDIVWC YFRLEQLECL DDAEKKLNLA QKCFKNCYGE NHQRLVHIKG NCGKEKVLFL RLYLLQGIRN YHSGNDVEAY EYLNKARQLF KELYIDPSKV DNLLQLGFTA QEARLGLRAC DGNVDHAATH ITNRREELAQ IRKEEKEKKR RRLENIRFLK GMGYSTHAAQ QILLSNPQMW WLNDSNPETD NRQESPSQEN IDRLVYMGFD ALVAEAALRV FRGNVQLAAQ TLAHNGGSLP PELPLSPEDS LSPPATSPSD SAGTSSASTD EDMETEAVNE ILEDIPEHEE DYLDSTLEDE EIIIAEYLSY VENRKSATKK N (252-601 aa encoded by BC046354)

Target Information

NYREN18 is a specific down-regulator of the NEDD8 conjugation system. It recruits NEDD8 and its conjugates to the proteasome for degradation. It also interacts with PSMD4/S5a, a member of the regulatory subunit of the 26S proteasome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Phosphorylated NUB1 distinguishes α-synuclein in Lewy bodies from that in glial cytoplasmic inclusions in multiple system atrophy.

Brain pathology (Zurich, Switzerland)

Tanji K,Miki Y,Mori F,Kon T,Kakita A,Takahashi H,Wakabayashi K

Fri Nov 01 00:00:00 EDT 2019

The role of NUB1 in α-synuclein degradation in Lewy body disease model mice.

Biochemical and biophysical research communications

Tanji K,Miki Y,Maruyama A,Mori F,Mimura J,Itoh K,Kamitani T,Wakabayashi K

Fri Feb 12 00:00:00 EST 2016

The role of NUB1 in α-synuclein degradation in Lewy body disease model mice.

Biochemical and biophysical research communications

Tanji K,Miki Y,Maruyama A,Mori F,Mimura J,Itoh K,Kamitani T,Wakabayashi K

Fri Feb 12 00:00:00 EST 2016

The role of NUB1 in α-synuclein degradation in Lewy body disease model mice.

Biochemical and biophysical research communications

Tanji K,Miki Y,Maruyama A,Mori F,Mimura J,Itoh K,Kamitani T,Wakabayashi K

Fri Feb 12 00:00:00 EST 2016

The role of NUB1 in α-synuclein degradation in Lewy body disease model mice.

Biochemical and biophysical research communications

Tanji K,Miki Y,Maruyama A,Mori F,Mimura J,Itoh K,Kamitani T,Wakabayashi K

Fri Feb 12 00:00:00 EST 2016

Ubiquitin-negative, eosinophilic neuronal cytoplasmic inclusions associated with stress granules and autophagy: an immunohistochemical investigation of two cases.

Neuropathology : official journal of the Japanese Society of Neuropathology

Mori F,Watanabe Y,Miki Y,Tanji K,Odagiri S,Eto K,Wakabayashi K

Tue Apr 01 00:00:00 EDT 2014

Ubiquitin-negative, eosinophilic neuronal cytoplasmic inclusions associated with stress granules and autophagy: an immunohistochemical investigation of two cases.

Neuropathology : official journal of the Japanese Society of Neuropathology

Mori F,Watanabe Y,Miki Y,Tanji K,Odagiri S,Eto K,Wakabayashi K

Tue Apr 01 00:00:00 EDT 2014

Bioinformatics

Protein Aliases: NEDD8 ultimate buster 1; NEDD8 ultimate buster-1; Negative regulator of ubiquitin-like proteins 1; NY-REN-18 antigen; Protein BS4; Renal carcinoma antigen NY-REN-18

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Gene Aliases: 4931404D21Rik; 6330412F12Rik; BS4; NUB1; NUB1L; NY-REN-18; NYREN18

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UniProt ID: (Human) Q9Y5A7, (Mouse) P54729

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Entrez Gene ID: (Human) 51667, (Rat) 296731, (Mouse) 53312

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Function(s)

protein binding molecular_function

Process(es)

ubiquitin-dependent protein catabolic process biological_process protein ubiquitination positive regulation of proteasomal ubiquitin-dependent protein catabolic process response to interferon-gamma response to tumor necrosis factor

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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NUB1 Polyclonal Antibody

NUB1 Antibody (14343-1-AP) in WB

Product Details

14343-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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