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NUP35 Antibody (PA5-23372) in IHC (P)
Immunohistochemical analysis of NUP35 in formalin-fixed, paraffin-embedded human brain tissue using. Samples were incubated in NUP35 polyclonal antibody (Product # PA5-23372) using a dilution of 5 µg/mL. Isotype control (top left) and this antibody (bottom left, right).
Product Details
PA5-23372
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Dog,
Human,
Mouse,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A portion of amino acids 280-326 of human NUP35
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2540895
Target Information
Nucleoporin Nup35 or Mitotic phosphoprotein 44 is a nuclear protein known to be present on nuclear pore complex and is tightly associated with the nuclear membrane and lamina. This RNA associated protein belongs to the Nup53 family and has a MPPN (mitotic phosphoprotein N' end) domain. It has a small number of scattered phenylalanine-glycine repeats, but not the large domains seen in other nucleoporins. Though the exact function of NUP35 is yet to be revealed, it may function as a component of the nuclear pore complex (NPC) which are collectively referred to as nucleoporins (NUPs). It also may play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors, and may also play an important part in the association of MAD1, a transcriptional repressor with the NPC. NUP35 is widely expressed in most of the tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 35 kDa nucleoporin; Mitotic phosphoprotein 44; MP-44; Nuclear pore complex protein Nup53; nucleoporin 35kDa; Nucleoporin NUP35; Nucleoporin NUP53
Gene Aliases: 2310006I24Rik; 35kDa; 5330402E05Rik; MP-44; MP44; NO44; NP44; NUP35; NUP53
UniProt ID: (Human) Q8NFH5, (Mouse) Q8R4R6
Entrez Gene ID: (Bovine) 511248, (Dog) 478830, (Human) 129401, (Mouse) 69482
biological_process
regulation of transcription, DNA-templated
mRNA export from nucleus
tRNA export from nucleus
NLS-bearing protein import into nucleus
nuclear pore organization
mitotic nuclear envelope disassembly
regulation of glucose transport
viral process
protein sumoylation
viral transcription
gene silencing by RNA
transmembrane transport
intracellular transport of virus
regulation of cellular response to heat
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