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Neurokinin A Antibody (BS-0069R) in IHC (P)
Formalin-fixed and paraffin-embedded rat brain labeled with Anti-NKA/Neurokinin A Polyclonal Antibody, Unconjugated(bs-0069R) 1:200, overnight at 4°C, The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated(bs-0295G-Cy3)used at 1:200 dilution for 40 minutes at 37°C.
Product Details
BS-0069R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human NKA, amino acids 98-107.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The tachykinins belong to an evolutionary conserved family of peptide neurotransmitters that share the c-terminal sequence Phe-X-Gly-Leu-Met-NH2 and have an established role in neurotransmission. The mammalian tachykinins include substance P, neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: neurokinin 1; neurokinin 2; neurokinin A; neurokinin alpha; neuromedin L; neuropeptide gamma; neuropeptide K; PPT; preprotachykinin; preprotachykinin A; protachykinin; Protachykinin-1; substance K; substance P; Tachykinin (substance P, neurokinin A, neuropeptide K, neuropeptide gamma); tachykinin 1; tachykinin 2; tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)
Gene Aliases: 4930528L02Rik; Hs.2563; NK-1; NK1; NK2; NKA; NKNA; NPK; PPT-A; Ppt5fl; PPTA; PPTA3; RATPPTA3; SP; TAC; TAC1; TAC2
UniProt ID: (Human) P20366, (Rat) P06767, (Mouse) P41539
Entrez Gene ID: (Human) 6863, (Rat) 24806, (Mouse) 21333
positive regulation of acute inflammatory response
inflammatory response
positive regulation of cytosolic calcium ion concentration
tachykinin receptor signaling pathway
neuropeptide signaling pathway
cell-cell signaling
chemical synaptic transmission
insemination
long-term memory
regulation of blood pressure
associative learning
detection of abiotic stimulus
response to hormone
negative regulation of heart rate
positive regulation of epithelial cell migration
sensory perception of pain
positive regulation of synaptic transmission, cholinergic
positive regulation of synaptic transmission, GABAergic
response to lipopolysaccharide
positive regulation of renal sodium excretion
response to morphine
positive regulation of action potential
positive regulation of ossification
positive regulation of saliva secretion
response to pain
positive regulation of lymphocyte proliferation
positive regulation of stress fiber assembly
cellular response to nerve growth factor stimulus
positive regulation of corticosterone secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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